CAS No. 21645-51-2

Batch: Purity:98
Aluminium hydroxide Chemical Structure
Chemical Structure
Check the Aluminium hydroxide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 21645-51-2
Molecular Formula

AlH3O3

Molecular Weight (MW) 78
SMILES O[Al](O)O

Ordering Information

Biological Activity

Aluminium hydroxide is an inorganic compound that acts as a vaccine adjuvant by stimulating innate immune pathways. It promotes the activation of the NLRP3 inflammasome complex, leading to the processing and secretion of pro-inflammatory cytokines including interleukin-1β (IL-1β) and IL-18. This inflammatory signaling cascades down to drive antigen presentation, facilitating robust adaptive immune responses and antigen-specific antibody production. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.