CAS No. 13707-88-5
Batch:
Purity:
Chemical Structure
Check the
Alprenolol hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 13707-88-5 | |
|---|---|---|
| Molecular Formula |
C15H24ClNO2 |
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| Molecular Weight (MW) | 285.81 | |
| SMILES | CC(C)NCC(COC1=CC=CC=C1CC=C)O.Cl |
Alprenolol hydrochloride is a synthetic non-selective beta-adrenergic receptor antagonist. By competitively binding to beta-1 and beta-2 adrenergic receptors, it inhibits catecholamine-induced activation of adenylate cyclase, leading to decreased intracellular cyclic AMP (cAMP) accumulation. This blockade downregulates downstream protein kinase A (PKA) signaling, blunting sympathetic stimulation and inhibiting cardiac inotropic and chronotropic cellular responses associated with adrenergic activation. [1]
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All in vitro solubility values are batch-tested experimental data (non-literature values).
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Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.