CAS No. 115066-04-1
Chemical Structure
Check the
α-NETA
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | trimethyl-(3-naphthalen-1-yl-3-oxopropyl)azanium iodide | |
|---|---|---|
| CAS Number | 115066-04-1 | |
| Molecular Formula |
C16H20NO.I |
|
| Molecular Weight (MW) | 369.24 | |
| InChIKey | QZXMJYVXMZJOAO-UHFFFAOYSA-M |
α-NETA is a small-molecule inhibitor of choline acetyltransferase and antagonist of CMKLR1, ALDH1A1, and G9a histone methyltransferase. Modulation of these targets alters G protein-coupled receptor signaling and epigenetic histone methylation, suppressing downstream tumor cell proliferation and inflammatory cell chemoattraction. Consequently, α-NETA exhibits anti-cancer activity and potential therapeutic utility in neuroinflammatory and demyelinating disease models. [1][2]
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Note: Technical data last updated: Sep 1, 2026.