CAS No. 490-59-5
Batch:
Purity:98
Chemical Structure
Check the
Alloxazine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 490-59-5 | |
|---|---|---|
| Molecular Formula |
C10H6N4O2 |
|
| Molecular Weight (MW) | 214.18 | |
| SMILES | C1=CC=C2C(=C1)N=C3C(=N2)NC(=O)NC3=O |
Alloxazine is a selective adenosine receptor antagonist that exhibits approximately 10-fold higher selectivity for the adenosine A2B receptor over the adenosine A2A receptor. By blocking A2B receptor activation, it inhibits adenosine-stimulated cyclic AMP accumulation and downstream signaling cascades. Alloxazine is widely utilized as a selective pharmacological tool to investigate adenosine A2B receptor-mediated cellular responses and physiological pathways. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
2 mg/mL
(9.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.