CAS No. 39524-08-8
Batch:
Purity:99.4
Chemical Structure
Check the
Akebia saponin D
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 39524-08-8 | |
|---|---|---|
| Molecular Formula |
C47H76O18 |
|
| Molecular Weight (MW) | 929.10 |
Biological Activity
Akebia saponin D (Asperosaponin VI) is a natural triterpenoid saponin extracted from Dipsacus asper that acts as a bioactive agent promoting osteogenic differentiation and bone formation. It enhances bone marrow stromal cell differentiation by activating the p38 MAPK and ERK1/2 signaling pathways. This stimulation upregulates osteogenic transcription factors and markers, promoting matrix mineralization and bone fracture healing. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(107.63 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 75 mg/mL |
| Ethanol | 40 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.