SMILES:

FC(F)(F)OC1=CC=C2[NH]C(=NC2=C1)C3=NC=C(OCCOCCOC4=CN=C(C=C4)C5=NC6=C([NH]5)C=CC(=C6)OC(F)(F)F)C=C3
AI-10-49 Chemical Structure
Chemical Structure
Check the AI-10-49 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 6-(trifluoromethoxy)-2-[5-[2-[2-[[6-[6-(trifluoromethoxy)-1H-benzimidazol-2-yl]-3-pyridinyl]oxy]ethoxy]ethoxy]-2-pyridinyl]-1H-benzimidazole
CAS Number 1256094-72-0
Molecular Formula

C30H22F6N6O5
Molecular Weight (MW) 660.52
SMILES FC(F)(F)OC1=CC=C2[NH]C(=NC2=C1)C3=NC=C(OCCOCCOC4=CN=C(C=C4)C5=NC6=C([NH]5)C=CC(=C6)OC(F)(F)F)C=C3
InChIKey WJBSSBFGPKTMQQ-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 62 mg/mL (93.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 16 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.