Molecular Weight: 449.93 g/mol

ADAMTS-5 Inhibitor Chemical Structure
Chemical Structure
Check the ADAMTS-5 Inhibitor product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 90 mg/mL (200.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 11 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Chemical Information

CAS Number 929634-33-3
Molecular Formula

C16H11ClF3N3OS3
Molecular Weight (MW) 449.93
SMILES C[N]1N=C(C(=C1SCC2=CC=C(Cl)C=C2)\C=C3/SC(=S)NC3=O)C(F)(F)F

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Note: Technical data last updated: Sep 1, 2026.