CAS No. 24502-78-1
Batch:
Purity:99.44
Chemical Structure
Check the
Acetylshikonin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | [(1R)-1-(5,8-dihydroxy-1,4-dioxonaphthalen-2-yl)-4-methylpent-3-enyl] acetate | |
|---|---|---|
| CAS Number | 24502-78-1 | |
| Molecular Formula |
C18H18O6 |
|
| Molecular Weight (MW) | 330.33 | |
| SMILES | CC(=CCC(C1=CC(=O)C2=C(C=CC(=C2C1=O)O)O)OC(=O)C)C | |
| InChIKey | WNFXUXZJJKTDOZ-OAHLLOKOSA-N |
Acetylshikonin is a natural naphthoquinone compound isolated from the roots of Lithospermum erythrorhizoma that acts as a general cytochrome P450 inhibitor. It exhibits broad anti-cancer and anti-inflammatory activities by suppressing cytochrome P450 enzyme activity, inhibiting cell proliferation, and inducing apoptosis through modulation of intrinsic apoptotic pathways in various cancer cell lines.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
2 mg/mL
(6.05 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.