CAS No. 151988-33-9

Ac2-26 Chemical Structure
Chemical Structure
Check the Ac2-26 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 151988-33-9
Molecular Formula

C141H210N32O44S

Molecular Weight (MW) 3089.44

Ordering Information

Biological Activity

Ac2-26 is an annexin A1-mimetic peptide that acts as an agonist of formyl peptide receptor signaling. By activating formyl peptide receptors, it reduces neutrophil adhesion and emigration, promotes neutrophil detachment from activated endothelium, and accelerates mucosal epithelial wound repair. Furthermore, Ac2-26 downregulates AnxA1 expression and inhibits NF-κB and MAPK pathway activation, attenuating tissue inflammation. [1][2]

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Note: Technical data last updated: Sep 1, 2026.