Molecular Weight: 397.47 g/mol
Chemical Structure
Check the
A-443654
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
79 mg/mL
(198.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 79 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
| IUPAC Name | (2S)-1-(1H-indol-3-yl)-3-[[5-(3-methyl-2H-indazol-5-yl)-3-pyridinyl]oxy]propan-2-amine | |
|---|---|---|
| CAS Number | 552325-16-3 | |
| Molecular Formula |
C24H23N5O |
|
| Molecular Weight (MW) | 397.47 | |
| SMILES | CC1=N[NH]C2=CC=C(C=C12)C3=CC(=CN=C3)OCC(N)CC4=C[NH]C5=CC=CC=C45 | |
| InChIKey | YWTBGJGMTBHQTM-IBGZPJMESA-N |
Note: Technical data last updated: Sep 1, 2026.