CAS No. 106463-17-6
| CAS Number | 106463-17-6 | |
|---|---|---|
| Molecular Formula |
C20H28N2O5S·HCl |
|
| Molecular Weight (MW) | 444.97 | |
| SMILES | CCOC1=CC=CC=C1OCCNC(C)CC2=CC(=C(C=C2)OC)S(=O)(=O)N.Cl |
Tamsulosin hydrochloride is a potent and selective antagonist of alpha1A adrenoceptors located in the prostate and bladder neck. By selectively blocking alpha1A-adrenergic receptor signaling, it inhibits norepinephrine-stimulated smooth muscle contraction in lower urinary tract tissues. Downstream effects include reduced smooth muscle tone and tissue relaxation, which facilitates lower urinary tract function and supports smooth muscle modulation research.
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
89 mg/mL
(200.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
88 mg/mL
(197.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 17 mg/mL |
| Ethanol | 8 mg/mL |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- Tamsulosin hydrochloride Solubility in DMSO
- Tamsulosin hydrochloride Stock Solution
- Tamsulosin hydrochloride Storage
- Tamsulosin hydrochloride Stability
- Tamsulosin hydrochloride Molecular Weight
- Tamsulosin hydrochloride SMILES
- Tamsulosin hydrochloride Chemical Structure (2D and 3D)
- Tamsulosin hydrochloride SDS|MSDS