CAS No. 515-03-7
Batch:
Purity:99.59
Chemical Structure
Check the
Sclareol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 515-03-7 | |
|---|---|---|
| Molecular Formula |
C20H36O2 |
|
| Molecular Weight (MW) | 308.5 | |
| SMILES | CC1(CCCC2(C1CCC(C2CCC(C)(C=C)O)(C)O)C)C |
Sclareol is a natural labdane-type diterpene alcohol that exhibits cytotoxic and antiproliferative activities against various human cancer cell lines. It suppresses cell proliferation and triggers apoptosis in leukemic and colon cancer cells. Sclareol-induced apoptosis is accompanied by DNA fragmentation and cell cycle arrest, highlighting its potential role in modulating apoptotic pathways and inhibiting cancer growth.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
41 mg/mL
(132.9 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 20 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.