Clinical Trials

Numerous clinical trials spanning Early Phase 1 through Phase 4—encompassing completed, active, recruiting, and withdrawn protocols—evaluate rosuvastatin calcium across diverse indications and pharmacokinetic parameters. Sponsored by both pharmaceutical companies and academic institutions, these studies focus extensively on hypercholesterolemia, coronary artery disease, hypertension with hyperlipidemia, and non-alcoholic steatohepatitis, as well as drug interactions and pharmacokinetics in healthy volunteers and patients with HIV. Collectively, this research underscores the compound's established role in lipid management and cardiovascular disease risk reduction.

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT07232069 RECRUITING
Coronary Artery Disease Risk Factors Multiple; Coronary Artery Disease Progression; Prevention & Control; Premature Atherosclerosis
Duke University
 2026-07-21 PHASE3
NCT05155137 RECRUITING
Stroke; Cognitive Decline
Hospital Moinhos de Vento
 2021-12-20 PHASE3
NCT07799779 NOT_YET_RECRUITING
Acute Coronary Syndromes (ACS)
Seoul National University Bundang Hospital
 2026-09 PHASE4
NCT05832229 RECRUITING
Cirrhosis; Cirrhosis, Liver; Cirrhosis Early; Cirrhosis Due to Hepatitis B; Cirrhosis Advanced; Cirrhosis Infectious; Cirrhosis Alcoholic; Cirrhosis Due to Hepatitis C
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
 2023-12-07 PHASE2
NCT07307989 RECRUITING
Ischemic Stroke; Hypercholesteremia
Chang Gung Memorial Hospital
 2025-08-01 PHASE2
NCT06186037 RECRUITING
Coronary Artery Disease; Dyslipidemias; Primary Prevention
Saint Vincent's Hospital, Korea
 2024-02-01 PHASE4
NCT06785727 NOT_YET_RECRUITING
Ischemic Stroke; Transient Ischemic Attack
Prof. dr. Nathalie van der Velde
 2025-02-01 PHASE4
NCT07605130 NOT_YET_RECRUITING
Intracranial Arteriosclerosis; Cognitive Impairment
Peking Union Medical College Hospital
 2026-05-25 PHASE4
NCT07474649 NOT_YET_RECRUITING
Coronary Atherosclerosis; Mixed Dyslipidemia; Hypercholesterolemia
Daiichi Sankyo
 2026-08-15 PHASE3
NCT07568574 ENROLLING_BY_INVITATION
Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
Enhanced Emirates Limited
 2026-03-12
NCT07254221 NOT_YET_RECRUITING
Anthracycline-induced Cardiac Toxicity; Breast Cancer; Anthracycline Related Cardiotoxicity in Breast Cancer; Anthracycline-induced Cardiotoxicity
Shiraz University of Medical Sciences
 2026-02-01 PHASE4
NCT03016819 RECRUITING
Alveolar Soft Part Sarcoma; Leiomyosarcoma; Synovial Sarcoma; Soft-Tissue Sarcoma
Advenchen Laboratories, LLC
 2017-08-15 PHASE3
NCT06538649 RECRUITING
Crohn's Ileocolitis; Crohn Disease
Stanford University
 2024-12-12 EARLY_PHASE1
NCT05850091 ACTIVE_NOT_RECRUITING
Coronary Artery Disease
Massachusetts General Hospital
 2023-12-07 PHASE4
NCT07629999 RECRUITING
Healthy Volunteers
Bristol-Myers Squibb
 2026-07-13 PHASE1
NCT05614739 RECRUITING
Urinary Bladder Neoplasms; Neoplasm Metastasis; Ureteral Neoplasms
Eli Lilly and Company
 2023-01-12 PHASE1
NCT07619118 NOT_YET_RECRUITING
Hypercholesterolaemia
AstraZeneca
 2026-09-15 PHASE3
NCT07748273 NOT_YET_RECRUITING
Obesity & Overweight; Bariatric Surgery; Pharmacokinetics After Oral Intake; Drug Absorption
Hospital das Clínicas de Ribeirão Preto
 2026-08-02
NCT07504198 NOT_YET_RECRUITING
Peripheral Nerve Disease
Tanta University
 2026-03 PHASE2; PHASE3
NCT03169985 ACTIVE_NOT_RECRUITING
Coronary Artery Disease
Samsung Medical Center
 2017-07-12 PHASE4
NCT03127631 ACTIVE_NOT_RECRUITING
Prostate Cancer; Cardiovascular Disease
McMaster University
 2015-10-21
NCT07389304 NOT_YET_RECRUITING
Lipid Profile,Blood Pressure
Shaheed Benazir Bhutto University Sheringal Dir Upper
 2026-03-01 PHASE1
NCT06982131 RECRUITING
Overweight; Obesity
Hoffmann-La Roche
 2025-06-04 PHASE1
NCT07565441 NOT_YET_RECRUITING
ADPKD (Autosomal Dominant Polycystic Kidney Disease)
Jemincare
 2026-05-11 PHASE1
NCT07446400 RECRUITING
Healthy Volunteers
Otsuka Pharmaceutical Development & Commercialization, Inc.
 2026-03-31 PHASE1
NCT06772168 RECRUITING
Dyslipidemia; Type 2 Diabetes
CMG Pharmaceutical Co. Ltd
 2024-04-19 PHASE3
NCT04903223 RECRUITING
Cholesterol; Lipidosis
Children's Mercy Hospital Kansas City
 2021-04-01 PHASE1
NCT07218900 ACTIVE_NOT_RECRUITING
Dyslipidaemia
AstraZeneca
 2025-11-13 PHASE2
NCT05910476 ACTIVE_NOT_RECRUITING
Coronary Artery Disease; Dyslipidemias
Yonsei University
 2023-05-03 PHASE4
NCT04499859 RECRUITING
Myocardial Infarction; Statin Adverse Reaction; HMG-CoA Reductase Inhibitor Toxicity
Kiyuk Chang, MD,PhD
 2020-10-01 PHASE4
NCT07128888 RECRUITING
Obesity or Overweight
Gan & Lee Pharmaceuticals.
 2025-11-17 PHASE1
NCT06317051 ACTIVE_NOT_RECRUITING
HIV Infections; Weight Gain
Kirby Institute
 2024-12-16 PHASE3
NCT07515339 WITHDRAWN
Chronic Kidney Disease
Bayer
 2026-04-08 PHASE1
NCT07316608 COMPLETED
Healthy Participants
AstraZeneca
 2026-03-16 PHASE1
NCT07692685 COMPLETED
Drug Drug Interaction; Pharmacokinetic Profiles; Safty
Neurodawn Pharmaceutical Co., Ltd.
 2026-05-07 PHASE1
NCT06231966 RECRUITING
Peripheral Artery Disease; Polyvascular Disease
Yonsei University
 2024-04-22
NCT06717269 COMPLETED
Healthy Volunteer
Nurix Therapeutics, Inc.
 2024-11-30 PHASE1
NCT07255820 COMPLETED
Type 2 Diabetes Mellitus; Hypercholesterolemia / Elevated LDL Cholesterol
Bahria University
 2026-01-01 PHASE4
NCT07349394 COMPLETED
Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
 2026-01-12 PHASE1
NCT06899061 ACTIVE_NOT_RECRUITING
Advanced Solid Malignancies
AstraZeneca
 2025-03-25 PHASE1
NCT07309042 NOT_YET_RECRUITING
Atherosclerotic Cardiovascular Diseases; Cerebrovascular Diseases
Beijing Inno Medicine Co., Ltd.
 2025-12 PHASE1
NCT07001787 NOT_YET_RECRUITING
Dyslipidemia
Jiangsu Hansoh Pharmaceutical Co., Ltd.
 2025-06 PHASE1
NCT06765265 RECRUITING
Acute Coronary Syndromes
King Edward Medical University
 2025-01-05 PHASE4
NCT06273215 UNKNOWN
Diabetes
Peking University Third Hospital
 2023-03-05 PHASE4
NCT06981299 COMPLETED
Healthy
Protego Biopharma Pty Ltd
 2025-05-29 PHASE1
NCT07215260 COMPLETED
Healthy
Boehringer Ingelheim
 2025-11-05 PHASE1
NCT07182383 COMPLETED
Healthy Subjects
Daiichi Sankyo
 2025-09-29 PHASE1
NCT07313124 COMPLETED
Cardiovascular Diseases (CVD)
Beni-Suef University
 2024-12-15 PHASE2; PHASE3
NCT04883840 TERMINATED
Ulcerative Colitis
Universitaire Ziekenhuizen KU Leuven
 2020-10-22 PHASE2; PHASE3
NCT06948747 COMPLETED
Healthy Participants
AstraZeneca
 2025-05-06 PHASE1
NCT06360120 RECRUITING
Ischemic Stroke
Kafrelsheikh University
 2024-04-10 PHASE3
NCT07011992 COMPLETED
Healthy Participants
Shionogi
 2025-07-18 PHASE1
NCT06834932 ACTIVE_NOT_RECRUITING
Dyslipidaemia
AstraZeneca
 2024-12-06 PHASE2; PHASE3
NCT06338293 RECRUITING
Coronary Artery Disease
Nanjing First Hospital, Nanjing Medical University
 2024-03-15 PHASE4
NCT06925854 COMPLETED
Healthy
AstraZeneca
 2025-04-17 PHASE1
NCT06917508 COMPLETED
RSV Infection; Drug Drug Interaction
Enanta Pharmaceuticals, Inc
 2025-03-13 PHASE1
NCT06949124 COMPLETED
Endometriosis; Uterine Fibroids; Assisted Reproduction
Jiangsu HengRui Medicine Co., Ltd.
 2025-04-28 PHASE1
NCT06813924 COMPLETED
Healthy Volunteers Sickle Cell Disease, Thalassemia
Novo Nordisk A/S
 2025-02-06 PHASE1
NCT06646354 ENROLLING_BY_INVITATION
Hypertension; Primary Hypercholesterolaemia
Hyundai Pharm
 2025-04-22 PHASE3
NCT06279234 COMPLETED
Type 2 Diabetes Mellitus (T2DM); Obesity
Pfizer
 2024-02-20 PHASE1
NCT04603508 UNKNOWN
Type 2 Diabetes Mellitus; Dyslipidemia
EMS
 2023-03 PHASE3
NCT06567327 COMPLETED
Obesity
Pfizer
 2024-08-28 PHASE1
NCT06594159 COMPLETED
Healthy
Eli Lilly and Company
 2024-10-22 PHASE1
NCT04098003 COMPLETED
Healthy Volunteers
Sony Tuteja
 2020-02-06 PHASE4
NCT06601517 NOT_YET_RECRUITING
Healthy Adult Subject; Overweight Subject
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
 2024-10 PHASE1
NCT06416800 COMPLETED
Healthy Participants
Incyte Corporation
 2024-06-19 PHASE1
NCT06503679 COMPLETED
Healthy
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
 2024-07-16 PHASE1
NCT06677957 COMPLETED
Healthy Participants
Genentech, Inc.
 2024-11-06 PHASE1
NCT06698666 RECRUITING
Major Depressive Disorder; MDD
Ain Shams University
 2022-10-01 PHASE3
NCT06504862 COMPLETED
Healthy
Boehringer Ingelheim
 2024-08-20 PHASE1
NCT06153433 UNKNOWN
Dyslipidemia
Yonsei University
 2023-11-06 PHASE4
NCT06910098 COMPLETED
LDL - Low Density Lipoprotein Receptor Disorder; Rosuvastatin
Central Park Medical College
 2023-12-01
NCT06105060 COMPLETED
Non-alcoholic Steatohepatitis
Beni-Suef University
 2023-12-17 EARLY_PHASE1
NCT05738291 COMPLETED
Healthy
Boehringer Ingelheim
 2023-05-01 PHASE1
NCT06329895 COMPLETED
Advanced Non-small Cell Lung Cancer; EGFR Mutation; HER2 Mutation; Healthy Volunteers
Bayer
 2024-03-25 PHASE1
NCT05747768 UNKNOWN
Chronic Kidney Disease
Peking University Third Hospital
 2022-07-15 PHASE4
NCT05926180 COMPLETED
Non-small Cell Lung Cancer
Dizal Pharmaceuticals
 2023-07-31 PHASE1
NCT06247748 COMPLETED
Diabetes Mellitus, Type 2; Overweight
Beijing Dongfang Biotech Co., Ltd.
 2023-10-19 PHASE1
NCT06293742 COMPLETED
Type 2 Diabetes Mellitus
Eccogene
 2024-02-08 PHASE1
NCT06111521 COMPLETED
Healthy
Eli Lilly and Company
 2023-10-27 PHASE1
NCT06162169 COMPLETED
Healthy Subjects
Allist Pharmaceuticals, Inc.
 2023-11-25 PHASE1
NCT07564726 COMPLETED
Hypertension; Hypercholesterolemia
Celltrion Pharm, Inc.
 2022-08-05 PHASE3
NCT05731596 UNKNOWN
Nonalcoholic Steatohepatitis
Tanta University
 2023-06 PHASE3
NCT03532139 COMPLETED
Ovarian Cancer
Beth Israel Deaconess Medical Center
 2018-07-25 PHASE2
NCT05884502 UNKNOWN
Dyslipidemias; Stroke, Acute Ischemic
Korea University Anam Hospital
 2022-09-01 PHASE4
NCT05615012 COMPLETED
Healthy Participants
Bristol-Myers Squibb
 2022-11-11 PHASE1
NCT06475872 COMPLETED
Primary Hypercholesterolemia; Combined Hyperlipidemia
Hanlim Pharm. Co., Ltd.
 2023-11-20 PHASE1
NCT06160414 Completed
Healthy
Alexion Pharmaceuticals Inc.
 2023-12-07 Phase 1
NCT06092931 COMPLETED
Healthy Participants
DICE Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company
 2023-10-16 PHASE1
NCT06191991 COMPLETED
Healthy Volunteers
Aligos Therapeutics
 2023-11-03 PHASE1
NCT05954624 COMPLETED
Drug Drug Interaction
Guangdong Raynovent Biotech Co., Ltd
 2023-07-10 PHASE1
NCT05981365 COMPLETED
Sickle Cell Disease
Pfizer
 2023-04-17 PHASE1
NCT03720366 COMPLETED
Leukemia, Myeloid, Acute
Celgene
 2018-10-04 PHASE1
NCT05338723 COMPLETED
Chemotherapy-induced Cardiotoxicity; Breast Cancer
Tanta University
 2020-09-15 PHASE3
NCT05788328 TERMINATED
Healthy
Pfizer
 2023-03-27 PHASE1
NCT03860220 COMPLETED
Hypertension; Dyslipidemias
Hyo-Soo Kim
 2019-04-25 PHASE4
NCT04542382 COMPLETED
Healthy Volunteers
University of California, San Francisco
 2021-10-28 PHASE1
NCT05898672 COMPLETED
Pharmacokinetics; Healthy Volunteers
Pfizer
 2023-06-09 PHASE1
NCT06053983 COMPLETED
Mi Q Wave
Rawalpindi Medical College
 2023-01-01 PHASE4
NCT05768360 COMPLETED
Healthy Male Subjects
AstraZeneca
 2023-04-25 PHASE1
NCT05742841 COMPLETED
Lipid Disorder
Wake Forest University Health Sciences
 2023-03-08 PHASE4
NCT04433533 UNKNOWN
Left Ventricular Diastolic Dysfunction; Hyperlipidemias
Yonsei University
 2021-01-06 PHASE4
NCT05787002 COMPLETED
Dyslipidemia
AstraZeneca
 2023-03-09 PHASE1
NCT04826354 COMPLETED
Atheroscleroses, Coronary
Korea University Anam Hospital
 2021-08-11 PHASE4
NCT05763459 COMPLETED
Healthy
Calico Life Sciences LLC
 2023-03-24 PHASE1
NCT05708573 COMPLETED
Healthy Participants
Alexion Pharmaceuticals, Inc.
 2023-02-01 PHASE1
NCT04964544 COMPLETED
High Cholesterol
AstraZeneca
 2021-07-08 PHASE3
NCT05652660 COMPLETED
Healthy
Pfizer
 2022-12-09 PHASE1
NCT03113994 TERMINATED
Spinal Cord Injuries; Osteoporosis; Metabolic Syndrome
Dr. B. Catharine. Craven
 2018-02-26 PHASE2
NCT03889314 UNKNOWN
Cardiovascular Risk Factor; Cardiovascular Diseases; Adverse Effect
Minneapolis Heart Institute Foundation
 2019-04-26 PHASE4
NCT04887194 COMPLETED
Advanced Solid Tumor
Mirati Therapeutics Inc.
 2021-04-08 PHASE1
NCT05637060 COMPLETED
Healthy Individuals
University of Karachi
 2022-11-24
NCT04744571 UNKNOWN
Coronary Artery Disease; Coronary Occlusion; Percutaneous Coronary Intervention; Chronic Total Occlusion of Coronary Artery; Drug-Eluting Stents
Beijing Anzhen Hospital
 2021-02
NCT05594615 COMPLETED
COVID-19
Enanta Pharmaceuticals, Inc
 2022-10-06 PHASE1
NCT05444556 COMPLETED
Healthy
Eli Lilly and Company
 2022-07-07 PHASE1
NCT05236530 COMPLETED
Malaria
Novartis Pharmaceuticals
 2022-03-09 PHASE1
NCT04974814 UNKNOWN
ST Elevation Myocardial Infarction
Beni-Suef University
 2021-05-26
NCT04303806 UNKNOWN
Preeclampsia
Assiut University
 2020-10 PHASE2
NCT05395117 COMPLETED
Healthy Participants
AstraZeneca
 2022-06-30 PHASE1
NCT04846231 COMPLETED
Hypercholesterolemia
The Cleveland Clinic
 2021-04-23 PHASE2
NCT03864042 COMPLETED
Advanced Solid Tumors; Metastatic Melanoma
Pfizer
 2018-01-02 PHASE1
NCT05072054 UNKNOWN
Heart Failure With Reduced Ejection Fraction
Post Graduate Institute of Medical Education and Research, Chandigarh
 2019-10-16 PHASE4
NCT03037372 UNKNOWN
HIV Infection
Makerere University
 2017-06-01 PHASE3
NCT03233243 COMPLETED
Cardiovascular Diseases; Atherosclerosis; Molecular Imaging
University of Coimbra
 2020-07-27 PHASE4
NCT04669041 COMPLETED
Hypercholesterolemia
Sanofi
 2020-12-08 PHASE3
NCT04659070 UNKNOWN
Primary Hypercholesterolemia; Hypertension
Hanlim Pharm. Co., Ltd.
 2020-07-15 PHASE3
NCT05368805 COMPLETED
Metastatic Colorectal Cancer
Hutchmed
 2022-03-02 PHASE1
NCT05176314 COMPLETED
Healthy
Loxo Oncology, Inc.
 2022-01-11 PHASE1
NCT04472611 COMPLETED
SARS-CoV-2
Yale University
 2020-10-30 PHASE3
NCT05076877 COMPLETED
Healthy
Janssen Research & Development, LLC
 2021-09-17 PHASE1
NCT02740699 TERMINATED
Cardiovascular Disease
National Heart, Lung, and Blood Institute (NHLBI)
 2016-04-11 PHASE4
NCT03044665 UNKNOWN
Cardiovascular Diseases; Cerebrovascular Disease; Peripheral Atherosclerotic Disease
Yonsei University
 2017-03-15
NCT03418974 UNKNOWN
Dyslipidemias
Fudan University
 2017-11-01 PHASE4
NCT04161001 UNKNOWN
Hypertension, Dyslipidemia
Daewoong Pharmaceutical Co. LTD.
 2019-11-20 PHASE3
NCT05045638 COMPLETED
Healthy Participants
Amgen
 2021-08-20 PHASE1
NCT03951207 COMPLETED
Dyslipidemias; Hypertension
Yuhan Corporation
 2019-05-30 PHASE4
NCT03993236 COMPLETED
Stroke, Ischemic
Keun-Sik Hong
 2019-09-09 PHASE4
NCT02569645 COMPLETED
Rectal Cancer
AHS Cancer Control Alberta
 2015-11 PHASE2
NCT05002244 COMPLETED
Health, Subjective
Celltrion
 2021-07-23 PHASE1
NCT04428086 COMPLETED
Solid Tumor, Adult
Jiangsu HengRui Medicine Co., Ltd.
 2020-07-27 PHASE1
NCT04817904 UNKNOWN
Cisplatin Adverse Reaction
Cairo University
 2020-11-17 PHASE2
NCT04889287 COMPLETED
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men
Bayer
 2021-05-26 PHASE1
NCT04749914 COMPLETED
Healthy
Eli Lilly and Company
 2021-02-15 PHASE1
NCT02901067 TERMINATED
Wounds and Injuries; Venous Thromboembolism
Denver Health and Hospital Authority
 2017-02-03 PHASE2
NCT04211272 COMPLETED
Healthy
Actelion
 2020-01-14 PHASE1
NCT04504851 UNKNOWN
Pulmonary Tuberculosis
National University Hospital, Singapore
 2020-08-12 PHASE2
NCT03907423 COMPLETED
Diabetes Mellitus, Type 2
Rehab Werida
 2019-04-01
NCT03510884 COMPLETED
Hypercholesterolaemia
Sanofi
 2018-05-31 PHASE3
NCT04158076 COMPLETED
Hypercholesterolemia; Hypertension
Addpharma Inc.
 2020-01-23 PHASE3
NCT04608344 COMPLETED
Rheumatoid Arthritis
Gilead Sciences
 2020-11-04 PHASE1
NCT04590937 COMPLETED
Healthy
Boehringer Ingelheim
 2020-10-20 PHASE1
NCT06094244 COMPLETED
Intracerebral Hemorrhage
Pomeranian Medical University Szczecin
 2017-03-17
NCT03720067 UNKNOWN
Cirrhosis; Portal Hypertension; Variceal Hemorrhage
Universidade Federal do Rio de Janeiro
 2019-01-25 PHASE2; PHASE3
NCT03847506 COMPLETED
Hypertension, Hyperlipidemia
HK inno.N Corporation
 2018-07-05 PHASE4
NCT02232360 UNKNOWN
Coronary Artery Disease
Gachon University Gil Medical Center
 2014-01 PHASE4
NCT02586155 COMPLETED
Diabetes Mellitus, Type 2; Coronary Artery Disease
Resverlogix Corp
 2015-11 PHASE3
NCT04515628 COMPLETED
Healthy Participants
Bristol-Myers Squibb
 2020-08-02 PHASE1
NCT05197517 COMPLETED
Bioequivalence
Rania Mahmoud Mohamed
 2020-09-21 PHASE1
NCT03529253 UNKNOWN
Coronary Artery Disease; Angina Pectoris
Kobe University
 2018-04-01 PHASE4
NCT04257032 COMPLETED
Healthy
Boehringer Ingelheim
 2020-02-13 PHASE1
NCT02662894 WITHDRAWN
Hypertension; Dyslipidemia
EMS
 2019-10 PHASE3
NCT04252300 COMPLETED
Drug Interactions
Bayer
 2020-03-02 PHASE1
NCT03597412 COMPLETED
Atherosclerotic Cardiovascular Disease; Type 2 Diabetes Mellitus
Yuhan Corporation
 2018-10-17 PHASE4
NCT04253353 COMPLETED
Healthy Volunteers
Pfizer
 2020-02-06 PHASE1
NCT04074551 COMPLETED
Hypertension; Dyslipidemias
Hanmi Pharmaceutical Company Limited
 2019-07-16 PHASE3
NCT04231435 COMPLETED
Healthy Volunteers
Celgene
 2019-12-18 PHASE1
NCT03510715 COMPLETED
Hypercholesterolemia
Sanofi
 2018-08-31 PHASE3
NCT02679664 UNKNOWN
Venous Thromboembolism
Ottawa Hospital Research Institute
 2016-11 PHASE2
NCT04124003 COMPLETED
Healthy Participants
Bristol-Myers Squibb
 2019-10-08 PHASE1
NCT03526367 WITHDRAWN
Contrast-induced Acute Kidney Injury; ST Elevation Myocardial Infarction; Primary PCI; Rosuvastatin; Hydration
Shenyang Northern Hospital
 2019-02-20 PHASE4
NCT04099732 COMPLETED
Healthy
Boehringer Ingelheim
 2019-10-07 PHASE1
NCT03954366 COMPLETED
Neoplasms
pharmaand GmbH
 2019-04-25 PHASE1
NCT02117453 COMPLETED
ANCA-associated Primary Necrotizing Vasculitides
Assistance Publique - Hôpitaux de Paris
 2014-10-27 PHASE3
NCT03355027 UNKNOWN
Atherosclerosis; Cardiovascular Diseases
Cambridge University Hospitals NHS Foundation Trust
 2017-11-30
NCT02008786 TERMINATED
Coronary Artery Dissection, Spontaneous
Cardiology Research UBC
 2014-06 PHASE4
NCT03434613 COMPLETED
Nonalcoholic Fatty Liver Disease; Dyslipidemias
Yonsei University
 2018-05-14 PHASE4
NCT04008186 COMPLETED
Healthy Adult Subjects
Biogen
 2019-06-14 PHASE1
NCT05306990 COMPLETED
Hydroxymethylglutaryl-CoA Reductase Inhibitors; Diabetes Mellitus
Helwan University
 2017-04-20
NCT03474562 COMPLETED
ASCVD; Impaired Fasting Glucose; Hypertension
Yuhan Corporation
 2018-04-03 PHASE4
NCT02859480 UNKNOWN
Coronary Artery Disease; Coronary Disease; Cardiovascular Diseases
Korea University Anam Hospital
 2015-09 PHASE4
NCT02476006 COMPLETED
Hypercholesterolemia
Sanofi
 2015-06-23 PHASE3
NCT03217409 COMPLETED
Diabetes Mellitus and Hypercholesterolemia
Yuhan Corporation
 2017-08-10 PHASE4
NCT03446261 COMPLETED
Type 2 Diabetes Mellitus; Hypercholesterolemia
Yuhan Corporation
 2018-02-23 PHASE4
NCT03707899 COMPLETED
Hypertension With Dyslipidemia
Jeil Pharmaceutical Co., Ltd.
 2018-12-13 PHASE1
NCT02546323 COMPLETED
Atherosclerosis
AstraZeneca
 2015-09-17 PHASE3
NCT02772640 COMPLETED
Hypercholesterolemia
Collegium Medicum w Bydgoszczy
 2016-03 PHASE4
NCT04481789 COMPLETED
Healthy Adult Subjects
Shionogi
 2018-10-17 PHASE1
NCT02215174 TERMINATED
Statin Pharmacokinetics Pre and Post Gastric Bypass Surgery
University of California, San Francisco
 2015-02 PHASE1
NCT03772262 COMPLETED
Interaction Drug Food
Washington State University
 2018-04-05 EARLY_PHASE1
NCT03801733 COMPLETED
Drug Interaction Potentiation
Akebia Therapeutics
 2018-06-17 PHASE1
NCT02234492 COMPLETED
Human Immunodeficiency Virus (HIV); Cardiovascular Disease (CVD)
Ottawa Heart Institute Research Corporation
 2014-09 PHASE4
NCT03311841 COMPLETED
Renal Insufficiency
Merck Sharp & Dohme LLC
 2018-03-01 PHASE1
NCT03363815 COMPLETED
Heathy Volunteer
Celgene
 2017-12-04 PHASE1
NCT02984982 COMPLETED
Hypercholesterolemia; Acute Coronary Syndrome
Sanofi
 2016-11-15 PHASE4
NCT02594800 COMPLETED
Atherosclerosis
Second Affiliated Hospital, Zhejiang University, School of Medicine
 2015-12-21 PHASE4
NCT02458755 UNKNOWN
Stroke; Intracranial Atherosclerosis
Samsung Medical Center
 2012-02 PHASE4
NCT01813357 COMPLETED
HIV; Cardiovascular Disease
Bayside Health
 2013-07-02 PHASE4
NCT03009487 COMPLETED
Hypertension; Hyperlipidemias
Daewoong Pharmaceutical Co. LTD.
 2017-01 PHASE3
NCT02428374 UNKNOWN
Myocardial Fibrosis
Federal University of São Paulo
 2015-05 PHASE4
NCT02532309 UNKNOWN
Carotid Atherosclerosis
Wei Liu
 2015-04 PHASE4
NCT03074630 COMPLETED
Diabetes Mellitus, Type 2; Hypercholesterolemia
Amsterdam UMC, location VUmc
 2016-05 PHASE4
NCT03395470 COMPLETED
Metabolic Disease
Poxel SA
 2017-08-21 PHASE1
NCT02418884 UNKNOWN
Coronary Artery Disease
Sir Run Run Shaw Hospital
 2015-04 PHASE4
NCT02105623 TERMINATED
Coronary Arteriosclerosis
CHEOL WHAN LEE, M.D., Ph.D
 2014-06 PHASE4
NCT03753477 COMPLETED
Healthy
Daewoong Pharmaceutical Co. LTD.
 2017-12-22 PHASE1
NCT04895059 COMPLETED
Healthy
Laboratorios Silanes S.A. de C.V.
 2017-04-30 PHASE1
NCT02977065 COMPLETED
Dyslipidemias
Chong Kun Dang Pharmaceutical
 2017-03-23 PHASE2
NCT02364258 COMPLETED
Dyslipidemia
Children's Mercy Hospital Kansas City
 2014-07 PHASE1
NCT02748057 COMPLETED
Hypercholesterolemia; Familial Hypercholesterolemia
Organon and Co
 2016-05-18 PHASE3
NCT03359291 COMPLETED
Healthy Subjects
Actelion
 2017-11-03 PHASE1
NCT03339752 COMPLETED
Healthy Subjects
Idorsia Pharmaceuticals Ltd.
 2017-10-30 PHASE1
NCT03007524 UNKNOWN
Acute Coronary Syndrome
Nanjing First Hospital, Nanjing Medical University
 2016-07 PHASE4
NCT01816997 UNKNOWN
Diabetes
Taipei Veterans General Hospital, Taiwan
 2012-01 PHASE4
NCT02827903 COMPLETED
Type 2 Diabetes; Dyslipidemia
Jeil Pharmaceutical Co., Ltd.
 2016-01-15 PHASE3
NCT03536598 COMPLETED
Hypertension With Hyperlipidemia
HK inno.N Corporation
 2016-10-14 PHASE3
NCT03210532 COMPLETED
Hypertension; Dyslipidemia
Daewon Pharmaceutical Co., Ltd.
 2016-10-07 PHASE3
NCT02484027 UNKNOWN
Infarction, Anterior Cerebral Artery
Second Affiliated Hospital of Soochow University
 2015-09 PHASE4
NCT02982798 COMPLETED
Diabetes; Hyperlipidemia
Jeil Pharmaceutical Co., Ltd.
 2017-07-06 PHASE1
NCT03136237 COMPLETED
Hereditary Angioedema
BioCryst Pharmaceuticals
 2017-02-17 PHASE1
NCT03247140 COMPLETED
Hypertension With Dyslipidemia
Jeil Pharmaceutical Co., Ltd.
 2017-06-10 PHASE1
NCT03677297 COMPLETED
Adult Periodontitis
Dr. D. Y. Patil Dental College & Hospital
 2016-01-28 PHASE4
NCT03088254 COMPLETED
Dyslipidemia With Hypertension
Jeil Pharmaceutical Co., Ltd.
 2016-09-20 PHASE3
NCT02586129 COMPLETED
Dyslipidemia; Type II Diabetes
Yuhan Corporation
 2015-11-04 PHASE3
NCT02643784 UNKNOWN
Ischemic
RenJi Hospital
 2015-12 PHASE4
NCT03010475 COMPLETED
Diabetes; Healthy
Novo Nordisk A/S
 2017-01-05 PHASE1
NCT03192579 COMPLETED
Coronary Artery Disease Progression
Kobe University
 2013-07-26 PHASE4
NCT03187496 COMPLETED
NASH
Enanta Pharmaceuticals, Inc
 2017-05-11 PHASE1
NCT02979704 UNKNOWN
Hyperlipidemia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
 2016-09 PHASE2; PHASE3
NCT03116516 COMPLETED
Hypertension; Hyperlipidemia
Yuhan Corporation
 2017-04-21 PHASE1
NCT02963116 COMPLETED
High Risk Coronary Artery Disease
AstraZeneca
 2016-12-20 PHASE1
NCT02626234 COMPLETED
cMET-dysregulated Advanced Solid Tumors
Novartis Pharmaceuticals
 2015-12-08 PHASE1
NCT03204058 COMPLETED
Chronic Periodontitis
Government Dental College and Research Institute, Bangalore
 2016-02-10 PHASE2; PHASE3
NCT02749994 COMPLETED
Hypercholesterolemia
IlDong Pharmaceutical Co Ltd
 2016-04 PHASE3
NCT01899027 UNKNOWN
Arterial Hypertension
University of Roma La Sapienza
 2014-01 PHASE4
NCT02305862 UNKNOWN
Arteriosclerosis; Diabetes Mellitus; Lipid Disorder
Capital Medical University
 2013-01
NCT02593487 UNKNOWN
Hyperlipemia; Coronary Heart Disease
Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
 2015-11 PHASE4
NCT02854527 COMPLETED
Healthy
Boehringer Ingelheim
 2016-08-22 PHASE1
NCT02995720 COMPLETED
Hypertension, Hyperlipidemia
Boryung Pharmaceutical Co., Ltd
 2016-08-26 PHASE1
NCT02433288 COMPLETED
Dyslipidemia; Hyperlipidemia
AstraZeneca
 2015-07-20
NCT02262143 COMPLETED
Mixed Dyslipidemias
IlDong Pharmaceutical Co Ltd
 2014-11 PHASE3
NCT02951962 COMPLETED
Hypertension; Hyperlipidemia
Yuhan Corporation
 2016-08 PHASE1
NCT02814500 UNKNOWN
Healthy
Alvogen Korea
 2016-07 PHASE1
NCT02106767 COMPLETED
Healthy
University of California, San Francisco
 2014-11 PHASE1
NCT02770261 COMPLETED
Hypertension; Cholesterolemia
Alvogen Korea
 2015-12 PHASE3
NCT02082665 COMPLETED
Cancer
GlaxoSmithKline
 2015-02-19 PHASE1
NCT01524653 COMPLETED
Venous Thromboembolism; Deep Vein Thrombosis; Neoplasms
University of Vermont
 2012-03 PHASE2
NCT02789475 UNKNOWN
Hypertension; Hyperlipidemias
Alvogen Korea
 2016-05 PHASE1
NCT02411903 UNKNOWN
Cerebral Infarction; Clopidogrel,Poor Metabolism of (Disorder)
The Third Affiliated Hospital of Guangzhou Medical University
 2015-03 PHASE4
NCT01870804 COMPLETED
Acute Coronary Syndrome
Centro Cardiopatici Toscani
 2013-05 PHASE4
NCT02985099 COMPLETED
Chronic Periodontitis; Type2 Diabetes
Government Dental College and Research Institute, Bangalore
 2015-11 PHASE2; PHASE3
NCT02420899 UNKNOWN
Acute Coronary Syndrome
Beijing Friendship Hospital
 2015-04
NCT02611518 COMPLETED
Healthy
Janssen Research & Development, LLC
 2016-04-05 PHASE1
NCT02704702 COMPLETED
Hypertension
Boryung Pharmaceutical Co., Ltd
 2016-03 PHASE1
NCT02767310 COMPLETED
Healthy
Verisfield UK Ltd. Greek Branch
 2016-05 PHASE1
NCT02608242 TERMINATED
Hypertension; Hyperlipidemia
Yuhan Corporation
 2015-11 PHASE1
NCT02709187 COMPLETED
Healthy
Alvogen Korea
 2016-03 PHASE1
NCT02671097 COMPLETED
Healthy Volunteers; Pharmacokinetics; Drug Interaction
Bayer
 2016-02 PHASE1
NCT02390375 COMPLETED
Hypercholesterolemia
Daewon Pharmaceutical Co., Ltd.
 2014-11 PHASE3
NCT02670070 UNKNOWN
Healthy
LG Life Sciences
 2016-03 PHASE1
NCT03715101 COMPLETED
Elderly
Seoul National University Hospital
 2015-04 PHASE1
NCT03026933 COMPLETED
Dyslipidemias
Kuhnil Pharmaceutical Co., Ltd.
 2014-05 PHASE3
NCT02126358 COMPLETED
Type 2 Diabetes; Dyslipidemia
LG Life Sciences
 2014-05 PHASE3
NCT02685462 COMPLETED
Healthy
Tobira Therapeutics, Inc.
 2016-01-31 PHASE1
NCT02800902 COMPLETED
Chronic Periodontitis
Government Dental College and Research Institute, Bangalore
 2015-05 PHASE2; PHASE3
NCT02574845 COMPLETED
Healthy
Boehringer Ingelheim
 2015-10-12 PHASE1
NCT02569814 COMPLETED
Hypertension; Hyperlipidemia
Boryung Pharmaceutical Co., Ltd
 2015-09 PHASE1
NCT00468923 COMPLETED
Cardiovascular Disease; Stroke
Population Health Research Institute
 2007-05 PHASE4
NCT02185963 COMPLETED
Diabetes
Seoul National University Bundang Hospital
 2014-10 PHASE4
NCT02077257 UNKNOWN
Acute Coronary Syndrome
Committee of Cardio-Cerebral-Vascular Diseases of GSC
 2014-03 PHASE4
NCT01881971 COMPLETED
HIV Seropositivity
Alison Morris
 2013-05 EARLY_PHASE1
NCT02933658 COMPLETED
Hypertension and Dyslipidemia
Daewon Pharmaceutical Co., Ltd.
 2015-11 PHASE1
NCT00923676 UNKNOWN
Sexual Dysfunction; Hyperlipidemia
University of Campania Luigi Vanvitelli
 2008-04 PHASE4
NCT02546648 COMPLETED
Atherosclerotic Disease; Perioperative Bleeding
McMaster University
 2015-02 PHASE3
NCT02542969 COMPLETED
Healthy
Madrigal Pharmaceuticals, Inc.
 2015-09 PHASE1
NCT02561884 UNKNOWN
Healthy
Daewoong Pharmaceutical Co. LTD.
 2015-10 PHASE1
NCT01697735 TERMINATED
Dyslipidemias
Wenzhou Medical University
 2012-09 PHASE4
NCT02371603 COMPLETED
Anaemia
GlaxoSmithKline
 2015-02-11 PHASE1
NCT03571087 COMPLETED
Primary Hypercholesterolemia
Hanlim Pharm. Co., Ltd.
 2014-09 PHASE3
NCT02226198 COMPLETED
Homozygous Familial Hypercholesterolemia (HoFH)
AstraZeneca
 2014-11 PHASE3
NCT02707224 COMPLETED
Healthy
Alvogen Korea
 2015-01 PHASE1
NCT02280590 COMPLETED
Hyperlipidemia
Dong-A ST Co., Ltd.
 2014-09 PHASE4
NCT02600520 COMPLETED
Chronic Periodontitis
Government Dental College and Research Institute, Bangalore
 2014-11 PHASE2; PHASE3
NCT02106845 COMPLETED
Neoplasms
Bayer
 2014-04-22 PHASE1
NCT01837823 COMPLETED
Obstructive Coronary Artery Disease; Coronary Artery Disease
Icahn School of Medicine at Mount Sinai
 2013-07 PHASE2
NCT02387619 COMPLETED
Hypertension; Hyperlipidemia
Jeil Pharmaceutical Co., Ltd.
 2015-02 PHASE1
NCT02289430 COMPLETED
Healthy
NVP Healthcare
 2014-12 PHASE1
NCT02231931 COMPLETED
Healthy
Boehringer Ingelheim
 2014-09-01 PHASE1
NCT02730689 COMPLETED
Healthy Volunteers
Alvogen Korea
 2014-12 PHASE1
NCT02445352 COMPLETED
Primary Hypercholesterolemia
Alvogen Korea
 2014-07 PHASE3
NCT00986999 TERMINATED
HIV Infections; Cardiovascular Disease
University of Hawaii
 2009-09 PHASE2; PHASE3
NCT03521700 COMPLETED
Renal Artery Obstruction; Stents; Lipids; Glomerular Filtration Rate; Blood Pressure
Chinese Academy of Medical Sciences, Fuwai Hospital
 2013-06-01 PHASE2; PHASE3
NCT01011478 TERMINATED
Colorectal Cancer; Precancerous Condition
NSABP Foundation Inc
 2010-03 PHASE3
NCT02087540 UNKNOWN
Hypertension; Hyperlipidemia
IlDong Pharmaceutical Co Ltd
 2013-05 PHASE3
NCT02284503 UNKNOWN
Non-ST-elevation Acute Coronary Syndromes
Shanghai Zhongshan Hospital
 2014-11 PHASE4
NCT01773512 UNKNOWN
Coronary Artery Disease
General University Hospital, Prague
 2012-06 PHASE4
NCT02612714 COMPLETED
Sexual Dysfunction
Chang Gung Memorial Hospital
 2013-07 PHASE4
NCT00913562 WITHDRAWN
Glaucoma; Diabetes
Medical University of Vienna
 2009-06 PHASE4
NCT01420549 COMPLETED
Hypercholesterolemia; Dyslipidemia
Ache Laboratorios Farmaceuticos S.A.
 2013-03 PHASE3
NCT02234882 COMPLETED
HIV Infections
ViiV Healthcare
 2014-09-05 PHASE1
NCT02233218 COMPLETED
Healthy Male Volunteer
Yuhan Corporation
 2014-07 PHASE1
NCT01935674 COMPLETED
HIV; Hypercholesterolaemia
Juan A. Arnaiz
 2013-09 PHASE4
NCT02125227 COMPLETED
Healthy
Yuhan Corporation
 2014-04 PHASE1
NCT02075619 COMPLETED
Hypertension
GlaxoSmithKline
 2014-03-24 PHASE1
NCT02369250 COMPLETED
Furcation Defects
Government Dental College and Research Institute, Bangalore
 2013-11 PHASE4
NCT01914432 COMPLETED
Hyperlipidemia; Hypertension
Yuhan Corporation
 2013-11 PHASE3
NCT01544309 COMPLETED
Hypercholesterolemia With Concomitant Type 2 Diabetes
Listen Trial Group
 2012-03
NCT03011775 COMPLETED
Adverse Effect; Atherosclerosis, Coronary; Insulin Resistance Syndrome
Ukrainian Medical Stomatological Academy
 2012-11 PHASE4
NCT02283515 COMPLETED
Chronic Periodontitis
Government Dental College and Research Institute, Bangalore
 2014-01 PHASE2; PHASE3
NCT02089399 COMPLETED
Healthy
Daewoong Pharmaceutical Co. LTD.
 2014-05 PHASE1
NCT01173939 TERMINATED
Hypercholesterolemia; Type 2 Diabetes; Hypertension
Positive Trial Group
 2010-07
NCT02089061 COMPLETED
Acute Coronary Syndromes
Bristol-Myers Squibb
 2014-03 PHASE1
NCT01170585 COMPLETED
Atherosclerosis; Systemic Lupus Erythematosus
Imperial College London
 2010-07 PHASE2
NCT01218802 COMPLETED
HIV Infections; Heart Disease
University Hospitals Cleveland Medical Center
 2011-02 PHASE2
NCT02101125 COMPLETED
Immunosuppression For Disease
Bristol-Myers Squibb
 2014-03 PHASE1
NCT01730040 COMPLETED
Hypercholesterolemia
Regeneron Pharmaceuticals
 2012-10 PHASE3
NCT02047175 COMPLETED
Hypertension; Hyperlipidemia
Chong Kun Dang Pharmaceutical
 2014-02 PHASE1
NCT02029625 COMPLETED
Dyslipidemia
NVP Healthcare
 2014-02 PHASE1
NCT01526460 COMPLETED
Platelet Dysfunction
IRCCS San Raffaele
 2011-08 PHASE2
NCT00929734 COMPLETED
Chronic Obstructive Pulmonary Disease (COPD)
University Hospital, Akershus
 2010-03 PHASE2
NCT02129231 COMPLETED
Oxidative Stress; Diabetic Polyneuropathy
University of Guadalajara
 2012-02 PHASE2
NCT05072405 COMPLETED
Drug Interaction
Chinese University of Hong Kong
 2013-01-11 PHASE4
NCT01968577 UNKNOWN
Coronary Artery Disease
Kleber Bomfim Araujo Martins
 2011-03 PHASE4
NCT01624857 UNKNOWN
Coronary Heart Disease
China National Center for Cardiovascular Diseases
 2012-06 PHASE3
NCT02737319 COMPLETED
Nephropathy
University of Sao Paulo
 2011-03 PHASE4
NCT01763866 COMPLETED
Hyperlipidemia
Amgen
 2013-01-15 PHASE3
NCT00979121 TERMINATED
Sepsis; Acute Lung Injury
National Heart, Lung, and Blood Institute (NHLBI)
 2010-01 PHASE3
NCT02011633 COMPLETED
Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
 2013-10 PHASE1
NCT02859129 COMPLETED
Hypertriglyceridemia
AstraZeneca
 2013-09 PHASE1
NCT01490398 COMPLETED
Hypertension; Cardiovascular Risk Factors
Asan Medical Center
 2011-12 PHASE4
NCT01874743 UNKNOWN
HIV-1 Infection
Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
 2012-03 PHASE2
NCT01870466 COMPLETED
Healthy
Samsung Medical Center
 2012-06 PHASE1
NCT01921946 COMPLETED
Hypertension
Boryung Pharmaceutical Co., Ltd
 2013-08 PHASE1
NCT01023607 COMPLETED
Coronary Artery Disease; Hyperlipidemia
Harbin Medical University
 2009-12 PHASE4
NCT01975194 TERMINATED
Stroke; Transient Ischemic Attack
Wayne State University
 2012-01 PHASE4
NCT01389388 COMPLETED
Carotid Artery Plaque; Ankylosing Spondylitis; Rheumatoid Arthritis
Diakonhjemmet Hospital
 2013-01
NCT01623921 UNKNOWN
Blunt Chest Trauma; Acute Respiratory Distress Syndrome
Tel-Aviv Sourasky Medical Center
 2012-08
NCT00505154 COMPLETED
Dilated Cardiomyopathy
Oslo University Hospital
 2007-07 PHASE3
NCT01153334 COMPLETED
ST-segment Elevation AMI
Yonsei University
 2010-08-02 PHASE4
NCT01863225 TERMINATED
Dyslipidemia; Coronary Artery Disease
Resverlogix Corp
 2013-05 PHASE2
NCT01764295 COMPLETED
Hypertension; Dyslipidemia
Daewoong Pharmaceutical Co. LTD.
 2012-09 PHASE3
NCT01469416 COMPLETED
Healthy
University of California, San Francisco
 2012-03 PHASE1
NCT01823133 COMPLETED
Healthy
LG Life Sciences
 2013-04 PHASE1
NCT01364220 TERMINATED
Stroke
Severance Hospital
 2010-08 PHASE3
NCT01382277 UNKNOWN
Hyperlipidemia; Coronary Artery Disease
Peking University First Hospital
 2011-03 PHASE4
NCT01711749 COMPLETED
Hypercholesterolaemia
GlaxoSmithKline
 2013-02-25 PHASE1
NCT01164540 WITHDRAWN
Venous Thrombosis; Pulmonary Embolism
AstraZeneca
 2011-02 PHASE3
NCT01775579 COMPLETED
Diabetes Mellitus
Hanmi Pharmaceutical Company Limited
 2013-01 PHASE1
NCT01795937 COMPLETED
Healthy
Boehringer Ingelheim
 2013-02 PHASE1
NCT01918332 COMPLETED
Hypertension,; Hyperlipidemia
LG Life Sciences
 2012-04 PHASE3
NCT01929070 COMPLETED
Healthy
Hanmi Pharmaceutical Company Limited
 2013-02 PHASE1
NCT01078675 COMPLETED
Familial Hypercholesterolaemia
AstraZeneca
 2010-02 PHASE3
NCT01466608 COMPLETED
Hypercholesterolemia
Seoul National University Hospital
 2011-11 PHASE4
NCT01646307 UNKNOWN
Focus of Study
Beijing Anzhen Hospital
 2012-01 PHASE4
NCT01725230 COMPLETED
Rheumatoid Arthritis
AstraZeneca
 2012-11 PHASE1
NCT01918358 COMPLETED
Hypertension; Hyperlipidemia
LG Life Sciences
 2012-12 PHASE1
NCT00951132 WITHDRAWN
Depression
University Hospital, Akershus
 2009-09 PHASE2
NCT01524601 COMPLETED
Disorder Related to Renal Transplantation; Hypercholesterolemia
University of Oslo School of Pharmacy
 2012-02 PHASE4
NCT01154036 COMPLETED
Hypercholesterolemia
Organon and Co
 2010-07 PHASE3
NCT01598363 COMPLETED
Healthy Volunteers
Biogen
 2012-06-30 PHASE1
NCT01971606 COMPLETED
A Total of 234 Patients With Acute Coronary Syndrome Who Will Undergo OPCAB.
Yonsei University
 2007-10 PHASE4
NCT01609907 COMPLETED
Hypertension; Hyperlipidemia
Yuhan Corporation
 2011-11 PHASE1
NCT01526317 COMPLETED
Pharmacokinetics and Drug Interaction of Crestor and Glucodown SR
Yuhan Corporation
 2011-12 PHASE1
NCT01350141 COMPLETED
Hypercholesterolemia; Dyslipidemia
Pfizer
 2011-06 PHASE2
NCT01548157 COMPLETED
Healthy
Hanmi Pharmaceutical Company Limited
 2012-03 PHASE1
NCT01494090 TERMINATED
Hip Fracture
University Hospital, Brest
 2011-08 PHASE3
NCT01823900 COMPLETED
Healthy
Severance Hospital
 2012-01 PHASE1
NCT01342211 COMPLETED
Hypercholesterolemia; Dyslipidemia
Pfizer
 2011-07 PHASE2
NCT01493856 COMPLETED
Healthy Volunteers
Daewoong Pharmaceutical Co. LTD.
 2012-01 PHASE1
NCT01936805 COMPLETED
Atherosclerosis
Yuksek Ihtisas Hospital
 2008-01 PHASE3
NCT01146483 COMPLETED
Drug Interaction Potentiation
Centre hospitalier de l'Université de Montréal (CHUM)
 2010-04 PHASE1
NCT01010516 UNKNOWN
Dyslipidemia
University of Ioannina
 2009-10 PHASE4
NCT01021488 UNKNOWN
Deep Vein Thrombosis; Venous; Thrombosis; Prevention
Hallym University Medical Center
 2009-10 PHASE4
NCT01489943 COMPLETED
Crohn's Disease
GlaxoSmithKline
 2011-09-19 PHASE1
NCT01918709 COMPLETED
Hypertension, Hyperlipidemia
LG Life Sciences
 2011-09 PHASE1
NCT00786136 COMPLETED
Diabetes Mellitus; Chronic Kidney Disease
Shenyang Northern Hospital
 2008-12 PHASE4
NCT01415466 COMPLETED
Healthy
Daewoong Pharmaceutical Co. LTD.
 2011-08 PHASE1
NCT00964106 COMPLETED
Drug Interactions
GlaxoSmithKline
 2009-08-26 PHASE1
NCT00990028 COMPLETED
Head Injury
Universidad Autonoma de San Luis Potosí
 2009-08 PHASE1; PHASE2
NCT00970606 TERMINATED
Acute Respiratory Distress Syndrome; Influenza; H1N1 Influenza
Gordon Bernard
 2009-10
NCT01105975 COMPLETED
Dyslipidemia
Eli Lilly and Company
 2010-04 PHASE2
NCT00620542 COMPLETED
Coronary Atherosclerosis
AstraZeneca
 2008-01 PHASE3
NCT04328064 COMPLETED
Behcet's Disease
University of Alexandria
 2010-05
NCT01288742 COMPLETED
Hepatitis C Virus
Tibotec Pharmaceuticals, Ireland
 2011-01 PHASE1
NCT00680017 COMPLETED
Dyslipidemia; Kidney Disease
AstraZeneca
 2008-06 PHASE3
NCT01414803 COMPLETED
Hyperlipidemia
Yonsei University
 2009-03 PHASE4
NCT00862251 COMPLETED
Cardiovascular Disorder; Diabetes Mellitus
Organon and Co
 2009-04 PHASE3
NCT01411111 COMPLETED
Asthma
GlaxoSmithKline
 2011-01-06 PHASE1
NCT00978419 COMPLETED
Burns
Vanderbilt University Medical Center
 2010-03 PHASE2
NCT01622777 COMPLETED
Diabetic Polyneuropathy
Alejandra Guillermina Miranda Diaz
 2010-02 PHASE2
NCT00487318 COMPLETED
Chronic Hepatitis C
Bader, Ted, M.D.
 2007-06 PHASE2
NCT01178853 COMPLETED
Healthy
Kowa Research Institute, Inc.
 2010-07 PHASE4
NCT01007279 COMPLETED
Periprocedural Myocardial Necrosis
University of Roma La Sapienza
 2010-03 PHASE3
NCT01183585 COMPLETED
Healthy Volunteer
Hoffmann-La Roche
 2010-08 PHASE1
NCT01138072 COMPLETED
Infection, Human Immunodeficiency Virus
GlaxoSmithKline
 2010-06 PHASE1
NCT00871351 COMPLETED
Primary Hypercholesterolemia
Organon and Co
 2009-02-01 PHASE4
NCT01033955 TERMINATED
Critically Ill; H1N1/Influenza Infection
Canadian Critical Care Trials Group
 2010-01 PHASE2
NCT00783263 COMPLETED
Hypercholesterolemia
Organon and Co
 2008-11 PHASE3
NCT00815659 COMPLETED
Metabolic Syndrome
AstraZeneca
 2008-12 PHASE4
NCT00987974 COMPLETED
Ischemia Reperfusion Injury; Endothelial Dysfunction
Radboud University Medical Center
 2009-09 PHASE4
NCT00555230 COMPLETED
Rheumatoid Arthritis
Chinese University of Hong Kong
 2007-07 PHASE2
NCT00718796 COMPLETED
Cardiovascular Disease
The Canadian College of Naturopathic Medicine
 2008-04 PHASE3
NCT00851175 COMPLETED
Atherosclerosis; Cardiovascular Disease
Radboud University Medical Center
 2009-03 PHASE4
NCT00747149 COMPLETED
Type 2 Diabetes
AstraZeneca
 2008-05 PHASE4
NCT01223625 COMPLETED
Endothelial Dysfunction; Atherosclerosis
Odense University Hospital
 2007-11 PHASE4
NCT01245894 COMPLETED
Myocardial Infarction [C14.907.585.500]
Odense University Hospital
 2007-11 PHASE4
NCT01547377 COMPLETED
Dietary Selenium Deficiency; Dietary Zinc Deficiency
Universidade Federal do Rio Grande do Norte
 2008-01
NCT00811356 TERMINATED
Malaria
GlaxoSmithKline
 2008-12-11 PHASE1
NCT00491530 COMPLETED
Mixed Dyslipidemia
Abbott
 2007-06 PHASE3
NCT00826358 COMPLETED
Healthy
AstraZeneca
 2008-11 PHASE1
NCT00240279 COMPLETED
Hypercholesterolemia
AstraZeneca
 2003-01 PHASE3
NCT00329160 COMPLETED
Hypercholesteremia
AstraZeneca
 2005-10 PHASE4
NCT00240331 COMPLETED
Renal Failure
AstraZeneca
 2003-01 PHASE3
NCT00800800 COMPLETED
Aortic Stenosis
AstraZeneca
 2002-11 PHASE3
NCT00719693 COMPLETED
Pharmacokinetic Variables
AstraZeneca
 2008-07 PHASE1
NCT00728780 COMPLETED
Adverse Events; Pharmacokinetic Variables
AstraZeneca
 2008-08 PHASE1
NCT00681395 COMPLETED
Adverse Events; Pharmacokinetic
AstraZeneca
 2008-05 PHASE1
NCT00355615 COMPLETED
Familial Hypercholesterolemia
AstraZeneca
 2006-07 PHASE3
NCT00395486 COMPLETED
Metabolic Syndrome X
AstraZeneca
 2006-09 PHASE4
NCT00462748 COMPLETED
Hypercholesterolemia
Organon and Co
 2007-03 PHASE3
NCT00336336 COMPLETED
Heart Failure
Gruppo di Ricerca GISSI
 2002-08 PHASE3
NCT00479713 COMPLETED
Hypercholesterolemia
Organon and Co
 2007-02-01 PHASE3
NCT00300430 COMPLETED
Dyslipidemia; Coronary Heart Disease; Mixed Dyslipidemia
Abbott
 2006-09 PHASE3
NCT00427960 TERMINATED
Hypercholesterolaemia
AstraZeneca
 2006-12 PHASE4
NCT00463606 COMPLETED
Hypercholesterolemia; Dyslipidemia
AstraZeneca
 2007-04 PHASE3
NCT00549653 COMPLETED
Atherosclerosis; Cardiovascular Disease
GlaxoSmithKline
 2007-10 PHASE1
NCT00329758 COMPLETED
Head Injury
Universidad Autonoma de San Luis Potosí
 2006-07 PHASE2
NCT00371579 WITHDRAWN
Hepatitis C
UMC Utrecht
 2006-10
NCT00665834 COMPLETED
Dyslipidemia; Acute Coronary Syndromes
Queen's University
 2006-04 PHASE4
NCT00457652 COMPLETED
Ischemia Reperfusion Injury
Radboud University Medical Center
 2007-06 PHASE4
NCT00214630 COMPLETED
Acute Coronary Syndromes
AstraZeneca
 2003-12 PHASE3
NCT00506961 COMPLETED
Diabetes Mellitus; Dyslipidemia
Taipei Veterans General Hospital, Taiwan
 2006-06 PHASE4
NCT00487136 COMPLETED
Healthy
AstraZeneca
 2007-06 PHASE1
NCT00206310 COMPLETED
Heart Failure
AstraZeneca
 2003-09 PHASE3
NCT00132717 COMPLETED
Hypercholesterolemia
Organon and Co
 2005-01-01 PHASE3
NCT00249912 COMPLETED
Hypercholesterolemia
Takeda
 2005-10 PHASE3
NCT00117494 COMPLETED
Hyperlipidemia; HIV Infections
French National Agency for Research on AIDS and Viral Hepatitis
 2005-10 PHASE4
NCT00214604 COMPLETED
Hyperlipoproteinemia Type III
AstraZeneca
 2005-02 PHASE3
NCT00693589 COMPLETED
Cardiovascular Disease; Endothelial Dysfunction
Insel Gruppe AG, University Hospital Bern
 2005-01 PHASE2
NCT00300482 COMPLETED
Dyslipidemia; Coronary Heart Disease; Mixed Dyslipidemia
Abbott
 2006-03 PHASE3
NCT00241488 COMPLETED
Hypercholesterolemia
AstraZeneca
 2003-06 PHASE3
NCT00240318 COMPLETED
Coronary Arteriosclerosis
AstraZeneca
 2002-11 PHASE3
NCT00651378 TERMINATED
Hypercholesterolemia; Atherosclerosis; Coronary Artery Disease
Organon and Co
 2004-09-01 PHASE4
NCT00239330 COMPLETED
Hypercholesteremia
AstraZeneca
 2003-06 PHASE3
NCT00090298 COMPLETED
Hypercholesterolemia
Organon and Co
 2004-04 PHASE3
NCT00240266 COMPLETED
Metabolic Syndrome; Dyslipidemia
AstraZeneca
 2003-08 PHASE3
NCT00651144 COMPLETED
Hypercholesterolemia; Atherosclerosis
Organon and Co
 2003-03 PHASE1
NCT00654602 COMPLETED
Dyslipidaemia
AstraZeneca
 2002-02 PHASE3
NCT00379249 COMPLETED
Hypercholesterolemia
AstraZeneca
 2002-02 PHASE3
NCT00335699 COMPLETED
Hypercholesterolemia
AstraZeneca
 2005-08 PHASE4
NCT00654407 COMPLETED
Hypercholesterolemia
AstraZeneca
 2001-11 PHASE3
NCT00388596 COMPLETED
Osteoporosis
GlaxoSmithKline
 2006-10 PHASE1
NCT00653588 COMPLETED
Hypercholesterolemia; Coronary Heart Disease
AstraZeneca
 2003-04 PHASE3
NCT00240305 COMPLETED
Metabolic Syndrome; Dyslipidemia
AstraZeneca
 2004-04 PHASE3
NCT00689416 COMPLETED
Atherosclerosis; Inflammatory Activity in Carotid Arteries
AstraZeneca
 2007-12 EARLY_PHASE1
NCT00654537 COMPLETED
Hypercholesterolemia
AstraZeneca
 2001-04 PHASE3
NCT00657527 COMPLETED
Myocardial Ischaemia; Coronary Artery Disease
AstraZeneca
 2001-12 PHASE3
NCT00079638 COMPLETED
Dyslipidemia; Coronary Heart Disease; Atherosclerosis; Stroke; Diabetes
Kos Pharmaceuticals
 2004-04 PHASE4
NCT00654394 COMPLETED
Carotid Artery Stenosis; Hypercholesterolemia
AstraZeneca
 2000-01 PHASE3
NCT00240292 COMPLETED
Heart Failure, Congestive
AstraZeneca
 2003-02 PHASE3
NCT00653965 COMPLETED
Hypercholesterolemia; Dyslipidaemia
AstraZeneca
 2003-05 PHASE3
NCT00160745 COMPLETED
Hypercholesterolemia
University of Erlangen-Nürnberg Medical School
 PHASE2
NCT00653445 COMPLETED
Hypercholesterolemia; Coronary Heart Disease; Atherosclerosis
AstraZeneca
 2004-06 PHASE3
NCT01203982 COMPLETED
ST-segment Elevation Myocardial Infarction; Subclinical Carotid Atherosclerosis
Odense University Hospital
 2007-11 PHASE4
NCT00654485 COMPLETED
Metabolic Syndrome
AstraZeneca
 2002-05 PHASE3
NCT00115830 COMPLETED
Atherosclerosis
Brigham and Women's Hospital
 2004-12 PHASE3
NCT00654173 COMPLETED
Hypercholesterolemia
AstraZeneca
 2002-06 PHASE3
NCT00309374 COMPLETED
Endotoxemia
Medical University of Vienna
 2006-03 PHASE1
NCT00214617 COMPLETED
Hypercholesterolemia
Foundation for Atlanta Veterans Education and Research, Inc.
 2005-01 PHASE4
NCT00329173 COMPLETED
Hypercholesterolaemia
AstraZeneca
 2003-11 PHASE3
NCT00783042 COMPLETED
Atherosclerosis; Inflammatory Activity in Coronary Arteries
AstraZeneca
 2008-10 EARLY_PHASE1
NCT00654303 COMPLETED
Hypercholesterolaemia
AstraZeneca
 1999-08 PHASE3
NCT00654225 COMPLETED
Hypercholesterolemia; Dyslipidaemia
AstraZeneca
 2002-10 PHASE3
NCT00766025 COMPLETED
CYP2C19 Poor; Extensive Metabolizers
AstraZeneca
 2008-09 PHASE1
NCT00176332 COMPLETED
Heart Failure
University of Leipzig
 2004-03 PHASE2

(data from https://clinicaltrials.gov, updated on 2026-09-01)

Check the Rosuvastatin calcium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Compliance for Clinical Use

Mechanism and Biochemical Profile

Rosuvastatin calcium competitively binds to and inhibits HMG-CoA reductase, thereby blocking the rate-limiting conversion of HMG-CoA to mevalonate and suppressing downstream hepatic cholesterol synthesis. This biochemical blockade reduces intracellular cholesterol levels and upregulates hepatic low-density lipoprotein receptors, enhancing systemic lipid clearance to provide clinical efficacy against hypercholesterolemia and coronary artery disease.

Appendix RUO and cGMP Quality Standards

Quality Dimension RUO (Research Use Only) cGMP (Current Good Manufacturing Practice)
Clinical Applicability Prohibited in human clinical trials or medical diagnostics. Mandatory for human clinical trials (Phase I–III) and therapies.
Regulatory Status Non-regulated grade; exempt from drug manufacturing laws. Legally enforced by health authorities (e.g., FDA, EMA, NMPA).
Facility Environment Unclassified analytical or research laboratories. Validated Cleanrooms (ISO Class 5–8) with continuous monitoring.
Quality Control Basic purity and activity testing. Rigorous safety release testing (Sterility, Endotoxin, Mycoplasma).
Process Validation Basic equipment calibration; no process validation required. Full qualification (IQ/OQ/PQ) and complete batch records.
Quality Assurance Vendor self-declared without required formal QMS. Mandatory QA/QC unit, Change Control, CAPA, and vendor audits.
Regulatory Impact High risk of IND rejection if used as a critical raw material. Required for IND/NDA filings, supported by Drug Master Files (DMF).

Footnotes

Regulatory Note: Governed by FDA (21 CFR Parts 210/211/312), EMA (EudraLex Vol 4), ICH Guidelines (E6/Q7/Q9/Q10), and compendial standards (USP <71>/<85>/<1043>).

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Note: Technical data last updated: Sep 1, 2026.