CAS No. 435-97-2
Batch:
Purity:99.51
Chemical Structure
Check the
Phenprocoumon
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-hydroxy-3-(1-phenylpropyl)chromen-2-one | |
|---|---|---|
| CAS Number | 435-97-2 | |
| Molecular Formula |
C18H16O3 |
|
| Molecular Weight (MW) | 280.32 | |
| SMILES | CCC(C1=CC=CC=C1)C2=C(C3=CC=CC=C3OC2=O)O | |
| InChIKey | DQDAYGNAKTZFIW-UHFFFAOYSA-N |
Phenprocoumon is a coumarin derivative and anticoagulant that acts as a vitamin K epoxide reductase inhibitor. By blocking vitamin K epoxide reductase activity, it disrupts the recycling of vitamin K, which prevents the post-translational gamma-carboxylation of clotting factors II, VII, IX, and X. This downstream suppression of functional coagulation factor synthesis impairs blood clotting pathways, leading to reduced thrombus formation and antithrombotic phenotypes. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
56 mg/mL
(199.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 56 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.