CAS No. 508-02-1

Batch: Purity:99.88
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Oleanolic Acid Chemical Structure
Chemical Structure
Check the Oleanolic Acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
CAS Number 508-02-1
Molecular Formula

C30H48O3
Molecular Weight (MW) 456.7
SMILES CC1(CCC2(CCC3(C(=CCC4C3(CCC5C4(CCC(C5(C)C)O)C)C)C2C1)C)C(=O)O)C
InChIKey MIJYXULNPSFWEK-GTOFXWBISA-N

Biological Activity

Oleanolic Acid is a naturally occurring pentacyclic triterpenoid with hepatoprotective, antitumor, and antiviral properties. It modulates cellular signaling networks by suppressing NF-kB activation and promoting the Nrf2 signaling pathway, thereby attenuating inflammatory responses and oxidative stress. Additionally, Oleanolic Acid inhibits cellular inflammatory processes and suppresses tumor cell proliferation across various cancer models.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 25 mg/mL (54.74 mM) ; Warmed with 60°C water bath ; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.