CAS No. 70458-96-7
Batch:
Purity:99.86
Chemical Structure
Check the
Norfloxacin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid | |
|---|---|---|
| CAS Number | 70458-96-7 | |
| Molecular Formula |
C16H18FN3O3 |
|
| Molecular Weight (MW) | 319.33 | |
| SMILES | CCN1C=C(C(=O)C2=CC(=C(C=C21)N3CCNCC3)F)C(=O)O | |
| InChIKey | OGJPXUAPXNRGGI-UHFFFAOYSA-N |
Norfloxacin is a broad-spectrum fluoroquinolone antibiotic targeting bacterial DNA gyrase and topoisomerase IV enzymes. By inhibiting these essential type II topoisomerases, norfloxacin prevents the separation of bacterial DNA strands and halts DNA replication, ultimately leading to the inhibition of cell division in both Gram-positive and Gram-negative bacteria. This targeted mechanism of action can also affect mammalian cell replication processes.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
3 mg/mL
(9.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| 0.5MNAOH | 3.02 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.