CAS No. 112885-42-4
| CAS Number | 112885-42-4 | |
|---|---|---|
| Molecular Formula |
C21H25ClFN3O3.C6H8O7 |
|
| Molecular Weight (MW) | 614.02 | |
| SMILES | CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
Mosapride Citrate is a selective 5-HT4 receptor agonist that functions as a gastroprokinetic agent. Activation of 5-HT4 receptors by Mosapride facilitates acetylcholine release from enteric cholinergic neurons, thereby enhancing gastrointestinal motility and accelerating gastric emptying. This mechanism supports its application in studying gastrointestinal motility disorders, including functional dyspepsia, acid reflux, and irritable bowel syndrome.
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
90 mg/mL
(146.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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