CAS No. 155-41-9

Batch: Purity:99.88
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Methscopolamine Chemical Structure
Chemical Structure
Check the Methscopolamine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 155-41-9
Molecular Formula

C18H24BrNO4
Molecular Weight (MW) 398.29
SMILES C[N+]1(C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4)C.[Br-]

Ordering Information

Biological Activity

Methscopolamine is a muscarinic acetylcholine receptor antagonist that acts as an anticholinergic agent. It competitively blocks acetylcholine from binding to muscarinic acetylcholine receptors, thereby inhibiting parasympathetic neurotransmission. By interfering with cholinergic signaling pathways, methscopolamine suppresses autonomic postganglionic signaling and disrupts impulse transmission within the emetic pathway, resulting in reduced smooth muscle contraction and diminished exocrine glandular secretions.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 80 mg/mL (200.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 80 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.