CAS No. 97792-45-5
| CAS Number | 97792-45-5 | |
|---|---|---|
| Molecular Formula |
C32H44N2O8.HBr |
|
| Molecular Weight (MW) | 665.61 | |
| SMILES | CCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5(C6OC)O)OC)O)OC)OC(=O)C7=CC=CC=C7NC(=O)C.Br |
Lappaconite hydrobromide is a natural diterpene alkaloid isolated from Aconitum sinomontanum Nakai that functions as an anti-inflammatory and analgesic agent targeting voltage-gated sodium channels. It inhibits neuronal sodium currents, thereby suppressing action potential propagation in sensory neurons and reducing nociceptive signaling. Furthermore, lappaconite hydrobromide demonstrates intestinal absorption across multiple intestinal segments and exerts anti-inflammatory activity through inhibition of pro-inflammatory signaling pathways. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
53 mg/mL
(79.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
53 mg/mL
(79.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.