CAS No. 4618-18-2

Batch: Purity:99.87
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Lactulose Chemical Structure
Chemical Structure
Check the Lactulose product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 4618-18-2
Molecular Formula

C12H22O11
Molecular Weight (MW) 342.3
SMILES C(C1C(C(C(C(O1)OC(C(CO)O)C(C(=O)CO)O)O)O)O)O

Biological Activity

Lactulose is a synthetic disaccharide composed of galactose and fructose that functions as an osmotic laxative and prebiotic growth stimulator for health-promoting gut microbiota. It selectively promotes the proliferation of beneficial intestinal bacteria, such as Bifidobacteria and Lactobacilli, while reducing luminal pH and decreasing systemic absorption of ammonia. Furthermore, lactulose suppresses monocyte activation to inhibit tumor necrosis factor (TNF) production and inflammatory signaling. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 68 mg/mL (198.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 68 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Reference

[1] Schumann C. Eur J Nutr. 2002;41 Suppl 1:I17-25.

[2] Panesar PS, et al. Biotechnol Adv. 2011;29(6):940-8.

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Note: Technical data last updated: Sep 1, 2026.