L-Rhamnose monohydrate

For research use only.

Catalog No.S3887 Synonyms: 6-deoxy-L-mannose monohydrate

L-Rhamnose monohydrate Chemical Structure

Molecular Weight(MW): 182.17

L-Rhamnose monohydrate is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.

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Biological Activity

Description L-Rhamnose monohydrate is used as a starting material for the production of furanones. It is an important material involved in the reaction of flavors developed during the preparation of various foods like bread, grilled meats, etc.
In vitro

L-rhamnose in concentration up to 20 (32 resp.) mmol/l can not be considered as cytotoxic or cytostatic for the used in vitro tumor models[1].

In vivo L-rhamnose exerts a significant suppressive effect on tumour growth. Its optimal dose is estimated to be 3.64 g/kg/day[2].

Protocol

Cell Research:[1]
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  • Cell lines: HL-60 cells
  • Concentrations: 0.125 mmol/l to 32 mmol/l
  • Incubation Time: 48 h
  • Method: At the beginning of the experiment, HL-60 cells are diluted to a concentration of 2x105/ml. Exponential growth of control cells is apparent during the observation interval. HL-60 cells are exposed to L-rhamnose or 2-deoxyglucose in final concentration from 0.125 mmol/l to 32 or 16 mmol/l, resp., in full cultivating medium.
    (Only for Reference)
Animal Research:[2]
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  • Animal Models: NMRI female mice
  • Dosages: 1, 3, or 5 g/kg/day
  • Administration: i.p.
    (Only for Reference)

Solubility (25°C)

In vitro DMSO 36 mg/mL (197.61 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 182.17
Formula

C6H12O5.H2O

CAS No. 6155-35-7
Storage powder
in solvent
Synonyms 6-deoxy-L-mannose monohydrate
Smiles O.CC1OC(O)C(O)C(O)C1O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID