CAS No. 22254-24-6
Batch:
Purity:100.00
Chemical Structure
Check the
Ipratropium Bromide
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 22254-24-6 | |
|---|---|---|
| Molecular Formula |
C20H30BrNO3 |
|
| Molecular Weight (MW) | 412.37 | |
| SMILES | CC(C)[N+]1(C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)C.[Br-] |
Ipratropium bromide is a muscarinic acetylcholine receptor antagonist that targets M3 muscarinic receptors. By inhibiting acetylcholine binding to cholinergic receptors in bronchial smooth muscle, it blocks parasympathetic pathway signaling and prevents muscle contraction. This blockade reduces airway smooth muscle tone, promotes bronchodilation, and antagonizes vagally induced bronchoconstriction in respiratory disease models. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
83 mg/mL
(201.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 83 mg/mL |
| Ethanol | 83 mg/mL |
| DMSO |
83 mg/mL
(201.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 83 mg/mL |
| Ethanol | 83 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Ipratropium Bromide Clinical Trials
- Ipratropium Bromide Solubility in DMSO
- Ipratropium Bromide Stock Solution
- Ipratropium Bromide Storage
- Ipratropium Bromide Stability
- Ipratropium Bromide Molecular Weight
- Ipratropium Bromide SMILES
- Ipratropium Bromide Chemical Structure (2D and 3D)
- Ipratropium Bromide SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.