CAS No. 25451-15-4
Batch:
Purity:99.96
Chemical Structure
Check the
Felbamate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 25451-15-4 | |
|---|---|---|
| Molecular Formula |
C11H14N2O4 |
|
| Molecular Weight (MW) | 238.24 | |
| SMILES | C1=CC=C(C=C1)C(COC(=O)N)COC(=O)N |
Felbamate is an anticonvulsant agent that functions as an N-methyl-D-aspartate (NMDA) receptor antagonist. By selectively inhibiting NMDA receptor-mediated responses through interaction with the glycine co-agonist binding site, felbamate effectively attenuates excitatory glutamate neurotransmission. Additionally, it potentiates GABA-A receptor-mediated inhibitory neurotransmission, suppressing neuronal hyperexcitability and reducing seizure activity across central nervous system networks. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
48 mg/mL
(201.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
| DMSO |
48 mg/mL
(201.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 3 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.