CAS No. 62-31-7

Batch: Purity:99.95
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Dopamine HCl Chemical Structure
Chemical Structure
Check the Dopamine HCl product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 4-(2-aminoethyl)benzene-1,2-diol;hydrochloride
CAS Number 62-31-7
Molecular Formula

C8H11NO2.HCl
Molecular Weight (MW) 189.64
SMILES C1=CC(=C(C=C1CCN)O)O.Cl
InChIKey CTENFNNZBMHDDG-UHFFFAOYSA-N

Ordering Information

Biological Activity

Dopamine HCl is an endogenous catecholamine neurotransmitter that acts as an agonist for dopamine D1, D2, D3, D4, and D5 receptors. As an immediate biosynthetic precursor to norepinephrine, it also stimulates adrenergic beta-1 and alpha receptors in a dose-dependent manner. Engagement of these receptors regulates intracellular cAMP levels and downstream signal transduction, modulating cardiovascular tone and neuronal signaling pathways. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 38 mg/mL (200.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 38 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.