CAS No. 635728-49-3
Batch:
Purity:99.92
Chemical Structure
Check the
Darunavir Ethanolate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;ethanol | |
|---|---|---|
| CAS Number | 635728-49-3 | |
| Molecular Formula |
C27H37N3O7S.C2H5OH |
|
| Molecular Weight (MW) | 593.73 | |
| SMILES | CCO.CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N | |
| InChIKey | QWSHKNICRJHQCY-VBTXLZOXSA-N |
Darunavir Ethanolate is a nonpeptidic HIV protease inhibitor designed to form robust interactions with the active site of HIV-1 protease. By inhibiting HIV-1 protease, it prevents the cleavage of viral Gag-Pol polyproteins, thereby blocking viral maturation and rendering newly released viral particles non-infectious. It exhibits potent antiviral activity against both wild-type HIV-1 and multidrug-resistant HIV-1 clinical isolates. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(168.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(168.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(168.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(168.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(168.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Darunavir Ethanolate Clinical Trials
- Darunavir Ethanolate Solubility in DMSO
- Darunavir Ethanolate Stock Solution
- Darunavir Ethanolate Storage
- Darunavir Ethanolate Stability
- Darunavir Ethanolate Molecular Weight
- Darunavir Ethanolate SMILES
- Darunavir Ethanolate Chemical Structure (2D and 3D)
- Darunavir Ethanolate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.