CAS No. 590-63-6

Batch: Purity:100.00
Check CoA
Bethanechol chloride Chemical Structure
Chemical Structure
Check the Bethanechol chloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-carbamoyloxypropyl(trimethyl)azanium chloride
CAS Number 590-63-6
Molecular Formula

C7H17N2O2.Cl
Molecular Weight (MW) 196.68
SMILES CC(C[N+](C)(C)C)OC(=O)N.[Cl-]
InChIKey XXRMYXBSBOVVBH-UHFFFAOYSA-N

Biological Activity

Bethanechol chloride is a selective muscarinic acetylcholine receptor agonist that exhibits no activity toward nicotinic receptors. As a parasympathomimetic choline ester resistant to cholinesterase hydrolysis, it provides sustained activation of muscarinic receptor signaling pathways. Agonism of muscarinic receptors stimulates G protein-coupled cascades, modulating intracellular calcium dynamics and smooth muscle tone, thereby serving as a valuable tool for studying cholinergic receptor function and parasympathetic responses. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 39 mg/mL (198.29 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 39 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Free Aliquotting Service

Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.

Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.

Reference

[1] Caulfield MP, et al. Pharmacol Rev. 1998;50(2):279-90.

[2] Wess J. Crit Rev Neurobiol. 1996;10(1):69-99.

Jump to

Note: Technical data last updated: Sep 1, 2026.