CAS No. 33570-04-6

Batch: Purity:99.55
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Bilobalide Chemical Structure
Chemical Structure
Check the Bilobalide product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 33570-04-6
Molecular Formula

C15H18O8
Molecular Weight (MW) 326.30
SMILES CC(C)(C)C1(CC2C3(C14C(C(=O)OC4OC3=O)O)CC(=O)O2)O

Ordering Information

Biological Activity

Bilobalide is a biologically active sesquiterpene trilactone constituent of Ginkgo biloba that acts as an antagonist at GABAA and GABAA-rho receptors. It exerts neuroprotective effects and induces hepatic cytochrome P450 enzymes, including CYP3A1 and CYP1A2. Through these actions, bilobalide modulates neuronal signaling pathways, attenuates neuronal damage, and alters xenobiotic metabolism. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 65 mg/mL (199.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 65 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.