CAS No. 83-46-5
Batch:
Purity:100.00
Chemical Structure
Check the
Beta-Sitosterol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | |
|---|---|---|
| CAS Number | 83-46-5 | |
| Molecular Formula |
C29H50O |
|
| Molecular Weight (MW) | 414.71 | |
| InChIKey | KZJWDPNRJALLNS-VJSFXXLFSA-N |
Beta-Sitosterol is a natural phytosterol that inhibits intestinal cholesterol absorption and modulates lipid metabolism. It incorporates into cellular membranes, competing with dietary and biliary cholesterol to suppress cellular sterol uptake. Consequently, Beta-Sitosterol attenuates intracellular cholesterol levels, alters membrane fluidity, and regulates downstream lipid signaling pathways to inhibit cancer cell proliferation and induce apoptosis. [1][2]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Ethanol | 5 mg/mL (超声加热五分钟，水浴60℃) |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| tert-Butanol | 50 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.