CAS No. 60-32-2

Batch: Purity:99.97
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(6-)ε-​Aminocaproic acid Chemical Structure
Chemical Structure
Check the (6-)ε-​Aminocaproic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 60-32-2
Molecular Formula

C6H13NO2
Molecular Weight (MW) 131.17
SMILES C(CCC(=O)O)CCN

Biological Activity

Aminocaproic acid is a lysine analogue and competitive inhibitor of plasminogen activation and plasmin activity. By binding to the lysine-binding sites of plasminogen, it prevents the interaction of plasminogen with fibrin, thereby suppressing fibrinolysis and stabilizing fibrin clot integrity. This compound inhibits proteolytic cleavage driven by plasmin, blocking downstream degradation of fibrin and associated extracellular matrix components. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 26 mg/mL
Ethanol 1 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.

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Reference

[1] ALKJAERSIG N, et al. J Biol Chem. 1959;234(4):832-7.

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Note: Technical data last updated: Sep 1, 2026.