CAS No. 17795-21-0

Batch: Purity:99.85
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Allopurinol Sodium Chemical Structure
Chemical Structure
Check the Allopurinol Sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium 1H-pyrazolo[5,4-d]pyrimidin-4-olate
CAS Number 17795-21-0
Molecular Formula

C5H4N4NaO
Molecular Weight (MW) 159.1
SMILES C1=NNC2=C1C(=NC=N2)[O-].[Na+]
InChIKey PTJRZVJXXNYNLN-UHFFFAOYSA-M

Biological Activity

Allopurinol sodium is a xanthine oxidase inhibitor that functions as a structural isomer of hypoxanthine. By targeting xanthine oxidase, it blocks the catalytic conversion of hypoxanthine and xanthine to uric acid. This inhibition suppresses uric acid accumulation and promotes the reutilization of xanthine and hypoxanthine for purine and nucleic acid synthesis, thereby reducing uric acid concentrations in cellular environments. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 31 mg/mL (194.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 31 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Pacher P, et al. Pharmacol Rev. 2006;58(1):87-114.

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Note: Technical data last updated: Sep 1, 2026.