CAS No. 76939-46-3
Batch:
Purity:99.99
Chemical Structure
Check the
8-Bromo-cAMP (8-Br-cAMP) Sodium Salt
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | sodium (4aR,6R,7R,7aS)-6-(6-amino-8-bromopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol | |
|---|---|---|
| CAS Number | 76939-46-3 | |
| Molecular Formula |
C10H10BrN5NaO6P |
|
| Molecular Weight (MW) | 430.08 | |
| SMILES | C1C2C(C(C(O2)N3C4=NC=NC(=C4N=C3Br)N)O)OP(=O)(O1)[O-].[Na+] | |
| InChIKey | DMRMZQATXPQOTP-GWTDSMLYSA-M |
8-Bromo-cAMP Sodium Salt is a cell-permeable cAMP analog that acts as a potent activator of cyclic-AMP-dependent protein kinase (PKA). Upon entering cells, it mimics endogenous cyclic AMP to bind and activate PKA, driving downstream phosphorylation of target substrates within the cAMP signaling pathway. This activation regulates key cellular processes, including gene expression, ion channel activity, metabolism, and cell proliferation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
86 mg/mL
(199.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 86 mg/mL |
| Ethanol | Insoluble |
| Water | 86 mg/mL |
| DMSO |
5 mg/mL
(11.62 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | Insoluble |
| DMSO |
86 mg/mL
(199.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 36 mg/mL |
| Ethanol | Insoluble |
| DMSO |
86 mg/mL
(199.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 86 mg/mL |
| Ethanol | Insoluble |
| DMSO |
125 mg/mL
(290.64 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Solubility in DMSO
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Stock Solution
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Storage
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Stability
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Molecular Weight
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt SMILES
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt Chemical Structure (2D and 3D)
- 8-Bromo-cAMP (8-Br-cAMP) Sodium Salt SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.