CAS No. 70500-72-0

Batch: Purity:99.88
7-Hydroxycarbostyril Chemical Structure
Chemical Structure
Check the 7-Hydroxycarbostyril product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 70500-72-0
Molecular Formula

C9H7NO2

Molecular Weight (MW) 161.16
SMILES C1=CC(=CC2=C1C=CC(=O)N2)O

Ordering Information

Biological Activity

7-Hydroxycarbostyril is a synthetic quinolinone derivative and key pharmaceutical intermediate widely utilized in medicinal chemistry for drug development. Quinolinone scaffolds serve as essential core structures in the synthesis of biologically active molecules targeting central nervous system receptors, particularly within G protein-coupled receptor signaling pathways. As a versatile heterocyclic building block, it enables the preparation of functionalized agents evaluated for dopamine receptor modulation and neuropharmacological research applications. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 32 mg/mL (198.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.