CAS No. 957-68-6
| CAS Number | 957-68-6 | |
|---|---|---|
| Molecular Formula |
C10H12N2O5S |
|
| Molecular Weight (MW) | 272.28 | |
| SMILES | CC(=O)OCC1=C(N2C(C(C2=O)N)SC1)C(=O)O |
7-Aminocephalosporanic acid is a core beta-lactam intermediate and precursor used for the synthesis of broad-spectrum cephalosporin antibiotics. Cephalosporin derivatives selectively target bacterial penicillin-binding proteins, inhibiting transpeptidase activity essential for peptidoglycan cross-linking during cell wall assembly. Blockade of peptidoglycan synthesis destabilizes the bacterial cell wall structural integrity, ultimately promoting osmotic lysis and cell death in susceptible bacterial strains. [1]
|
Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
1 mg/mL
(3.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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- 7-Aminocephalosporanic acid Solubility in DMSO
- 7-Aminocephalosporanic acid Stock Solution
- 7-Aminocephalosporanic acid Storage
- 7-Aminocephalosporanic acid Stability
- 7-Aminocephalosporanic acid Molecular Weight
- 7-Aminocephalosporanic acid SMILES
- 7-Aminocephalosporanic acid Chemical Structure (2D and 3D)
- 7-Aminocephalosporanic acid SDS｜MSDS