CAS No. 842-01-3

Batch: Purity:99.87
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7,8-Dihydroxy-4-phenylcoumarin Chemical Structure
Chemical Structure
Check the 7,8-Dihydroxy-4-phenylcoumarin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 842-01-3
Molecular Formula

C15H10O4
Molecular Weight (MW) 254.24
SMILES C1=CC=C(C=C1)C2=CC(=O)OC3=C2C=CC(=C3O)O

Ordering Information

Biological Activity

7,8-Dihydroxy-4-phenylcoumarin is a synthetic coumarin derivative and antioxidant intermediate that acts as a scavenger of reactive oxygen species. By modulating cellular redox status and reducing oxidative stress pathways, it helps protect cells against free radical-induced damage and lipid peroxidation. This polyphenolic compound suppresses oxidative cellular injury and supports downstream cellular survival phenotypes under oxidative stress conditions. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 51 mg/mL (200.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 51 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.