CAS No. 5006-66-6
Batch:
Purity:99.89
Chemical Structure
Check the
6-Hydroxynicotinic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 5006-66-6 | |
|---|---|---|
| Molecular Formula |
C6H5NO3 |
|
| Molecular Weight (MW) | 139.11 | |
| SMILES | C1=CC(=O)NC=C1C(=O)O |
6-Hydroxynicotinic acid is a pyridine derivative and a key metabolic intermediate in the microbial biodegradation pathway of nicotinic acid. It is generated via the regioselective hydroxylation of nicotinic acid by nicotinic acid hydroxylase and subsequently undergoes enzymatic transformation to yield essential cellular carbon and nitrogen sources. This metabolite plays an essential role in pyridine catabolic pathways across diverse bacterial species. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
5 mg/mL
(35.94 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 6-Hydroxynicotinic acid Solubility in DMSO
- 6-Hydroxynicotinic acid Stock Solution
- 6-Hydroxynicotinic acid Storage
- 6-Hydroxynicotinic acid Stability
- 6-Hydroxynicotinic acid Molecular Weight
- 6-Hydroxynicotinic acid SMILES
- 6-Hydroxynicotinic acid Chemical Structure (2D and 3D)
- 6-Hydroxynicotinic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.