CAS No. 19492-02-5
Batch:
Purity:99
Chemical Structure
Check the
6-Chloro-7-hydroxy-4-methylcoumarin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 19492-02-5 | |
|---|---|---|
| Molecular Formula |
C10H7ClO3 |
|
| Molecular Weight (MW) | 210.61 | |
| SMILES | CC1=CC(=O)OC2=CC(=C(C=C12)Cl)O |
6-Chloro-7-hydroxy-4-methylcoumarin is a chlorinated coumarin derivative and synthetic intermediate used in the development of bioactive molecules. Coumarin scaffolds serve as versatile pharmacophores exhibiting anti-inflammatory, antioxidant, and antimicrobial properties by modulating cellular signaling pathways. As a functionalized building block, it enables the synthesis of novel chemical entities that target key enzymatic pathways to suppress cellular proliferation and reactive oxygen species generation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
42 mg/mL
(199.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 6-Chloro-7-hydroxy-4-methylcoumarin Solubility in DMSO
- 6-Chloro-7-hydroxy-4-methylcoumarin Stock Solution
- 6-Chloro-7-hydroxy-4-methylcoumarin Storage
- 6-Chloro-7-hydroxy-4-methylcoumarin Stability
- 6-Chloro-7-hydroxy-4-methylcoumarin Molecular Weight
- 6-Chloro-7-hydroxy-4-methylcoumarin SMILES
- 6-Chloro-7-hydroxy-4-methylcoumarin Chemical Structure (2D and 3D)
- 6-Chloro-7-hydroxy-4-methylcoumarin SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.