CAS No. 82517-12-2

Batch: Purity:99.87
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5-Methyl-7-methoxyisoflavone Chemical Structure
Chemical Structure
Check the 5-Methyl-7-methoxyisoflavone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 82517-12-2
Molecular Formula

C17H14O3
Molecular Weight (MW) 266.29
SMILES CC1=CC(=CC2=C1C(=O)C(=CO2)C3=CC=CC=C3)OC

Biological Activity

5-Methyl-7-methoxyisoflavone is a synthetic isoflavone derivative that functions as a non-hormonal metabolic agent. The compound belongs to the isoflavone class, which influences intracellular signaling networks to regulate cellular protein accumulation and metabolic homeostasis. In cell-based models, isoflavone derivatives modulate estrogen receptor-mediated and nutrient-sensing signaling pathways to favor cellular nitrogen retention and protein synthesis while lacking classical androgenic activity. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 53 mg/mL (199.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Kuiper GG, et al. Endocrinology. 1998;139(10):4252-63.

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Note: Technical data last updated: Sep 1, 2026.