CAS No. 67-47-0
Batch:
Purity:99.78
Chemical Structure
Check the
5-Hydroxymethylfurfural
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 67-47-0 | |
|---|---|---|
| Molecular Formula |
C6H6O3 |
|
| Molecular Weight (MW) | 126.11 | |
| SMILES | C1=C(OC(=C1)C=O)CO |
5-Hydroxymethylfurfural (5-HMF) is an organic carbohydrate derivative and high-affinity hemoglobin modifier. It directly binds to sickle hemoglobin, increasing oxygen affinity and stabilizing the allosteric oxygenated state of the protein complex. Consequently, 5-HMF effectively inhibits red blood cell sickling, attenuates tissue hypoxia, and protects against hypoxemia-induced vascular occlusion and cellular oxidative stress under hypoxic physiological conditions. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
25 mg/mL
(198.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 5-Hydroxymethylfurfural Solubility in DMSO
- 5-Hydroxymethylfurfural Stock Solution
- 5-Hydroxymethylfurfural Storage
- 5-Hydroxymethylfurfural Stability
- 5-Hydroxymethylfurfural Molecular Weight
- 5-Hydroxymethylfurfural SMILES
- 5-Hydroxymethylfurfural Chemical Structure (2D and 3D)
- 5-Hydroxymethylfurfural SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.