CAS No. 3131-52-0
Batch:
Purity:99.72
Chemical Structure
Check the
5,6-Dihydroxyindole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 3131-52-0 | |
|---|---|---|
| Molecular Formula |
C8H7NO2 |
|
| Molecular Weight (MW) | 149.15 |
5,6-Dihydroxyindole is an indole derivative and a key monomer intermediate in the eumelanin biosynthesis pathway. It acts as a potent antioxidant that scavenges reactive oxygen species (ROS) and mitigates oxidative stress. Oxidation of 5,6-dihydroxyindole promotes melanin polymer formation, contributing to tissue pigmentation in skin, hair, and eyes while conferring cellular protection against oxidative damage. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
30 mg/mL
(201.13 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 30 mg/mL |
| Water | 8 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.