CAS No. 111843-78-8

5(6)-Carboxy-2',7'-dichlorofluorescein Chemical Structure 5(6)-Carboxy-2',7'-dichlorofluorescein Chemical Structure
Chemical Structure
Check the 5(6)-Carboxy-2',7'-dichlorofluorescein product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 111843-78-8
Molecular Formula

C21H10Cl2O7

Molecular Weight (MW) 445.21

Biological Activity

5(6)-Carboxy-2',7'-dichlorofluorescein is a fluorogenic derivative that acts as a probe substrate for multidrug resistance-associated protein 2 (MRP2/ABCC2). It serves as a functional fluorescent surrogate for leukotriene C4 (LTC4) in vesicular transport assays, enabling the quantitative assessment of MRP2-mediated ATP-dependent transport and efflux activity. This reagent facilitates the functional evaluation of ABC transporter kinetics and screening of potential MRP2 modulators in cell-free membrane preparations.

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Note: Technical data last updated: Sep 1, 2026.