SMILES:

COC1=C(NC(=O)NC2=NC3=C(S2)C=C(NC4=NC=NC5=CC(=C(OC)C=C45)OCCCN6CCN(C)CC6)C=C3)C=C(C)C=C1
4SC-203 Chemical Structure
Chemical Structure
Check the 4SC-203 product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 1-(2-methoxy-5-methylphenyl)-3-[6-[[6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-yl]amino]-1,3-benzothiazol-2-yl]urea
CAS Number 895533-09-2
Molecular Formula

C33H38N8O4S
Molecular Weight (MW) 642.77
SMILES COC1=C(NC(=O)NC2=NC3=C(S2)C=C(NC4=NC=NC5=CC(=C(OC)C=C45)OCCCN6CCN(C)CC6)C=C3)C=C(C)C=C1
InChIKey MAFACRSJGNJHCF-UHFFFAOYSA-N

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (155.57 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 12 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.