CAS No. 18979-61-8
Batch:
Purity:99.75
Chemical Structure
Check the
4-Butylresorcinol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-butylbenzene-1,3-diol | |
|---|---|---|
| CAS Number | 18979-61-8 | |
| Molecular Formula |
C10H14O2 |
|
| Molecular Weight (MW) | 166.22 | |
| SMILES | CCCCC1=C(C=C(C=C1)O)O | |
| InChIKey | CSHZYWUPJWVTMQ-UHFFFAOYSA-N |
4-Butylresorcinol is a potent synthetic inhibitor of tyrosinase and tyrosinase-related protein-1 (TRP-1). By directly inhibiting tyrosinase enzyme activity, it effectively blocks key enzymatic steps in the melanogenesis pathway, thereby suppressing melanin synthesis and reducing cellular pigmentation in human melanocytes. This compound targets melanogenic pathways to prevent melanin hyperproduction without inducing non-specific cytotoxicity. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
34 mg/mL
(204.54 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.