4-Biphenylacetic acid

Catalog No.S3685 Synonyms: BPA

4-Biphenylacetic acid Chemical Structure

Molecular Weight(MW): 212.24

4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.

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Biological Activity

Description 4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
In vitro

4-Biphenylacetic acid (BPAA) is a prostaglandin-synthesis inhibitor[1].

In vivo 4-Biphenylacetic acid (BPAA) markedly inhibits the ocular effects of both chemically and mechanically induced trauma[1].

Protocol

Solubility (25°C)

In vitro DMSO 42 mg/mL (197.88 mM)
Ethanol 42 mg/mL (197.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 212.24
Formula

C14H12O2

CAS No. 5728-52-9
Storage powder
in solvent
Synonyms BPA

Bio Calculators

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04052243 Not yet recruiting Diagnostic Test: Invasive exercise testing Chronic Thromboembolic Pulmonary Hypertension Aarhus University Hospital|Nagoya University|Department of Pulmonary Circulation and Thromboembolic Diseases Medical Center for Postgraduate Med January 1 2020 Not Applicable
NCT04099485 Not yet recruiting Other: Electronic Health Record Best Practice Advisory Atrial Fibrillation University of Cincinnati January 1 2020 Not Applicable
NCT03932487 Recruiting Other: urinary iodine and urine BPA The Effect of Iodine and BPA on AITD in Reproduction Women Xiaomei Zhang|Peking University International Hospital April 24 2019 --
NCT03361137 Recruiting Drug: Emicizumab Hemophilia A Genentech Inc. June 28 2018 Phase 4
NCT03245268 Recruiting Procedure: Balloon pulmonary angioplasty Chronic Thromboembolic Pulmonary Hypertension|CTEPH International CTEPH Association March 2 2018 --

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID