For research use only.
Catalog No.S3685 Synonyms: BPA
Molecular Weight(MW): 212.24
4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.
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|Description||4-Biphenylacetic acid (BPA) is a potential non-steroidal anti-inflammatory agent and forms solid inclusion complex with β-cyclodextrin. Its interaction with quinolone antibacterial agents can induce functional blockade of the γ-aminobutyric acid receptors.|
4-Biphenylacetic acid (BPAA) is a prostaglandin-synthesis inhibitor.
|In vivo||4-Biphenylacetic acid (BPAA） markedly inhibits the ocular effects of both chemically and mechanically induced trauma.|
|In vitro||DMSO||42 mg/mL (197.88 mM)|
|Ethanol||42 mg/mL (197.88 mM)|
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
In vivo Formulation Calculator (Clear solution)
|Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)|
|Dosage||mg/kg||Average weight of animals||g||Dosing volume per animal||ul||Number of animals|
|Step 2: Enter the in vivo formulation (Different batches have different solubility ratios, please contact Selleck to provide you with the correct ratio)|
|% DMSO % % Tween 80 % ddH2O|
Working concentration： mg/ml；
Method for preparing DMSO master liquid: ： mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL，)
Method for preparing in vivo formulation：Take DMSO master liquid, next addμL PEG300， mix and clarify, next addμL Tween 80，mix and clarify, next add μL ddH2O，mix and clarify.
1.Please make sure the liquid is clear before adding the next solvent.
2.Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Clinical Trial Information
|NCT Number||Recruitment||interventions||Conditions||Sponsor/Collaborators||Start Date||Phases|
|NCT04326777||Recruiting||Procedure: Ballon pulmonary angioplasty||Chronic Thromboembolic Pulmonary Hypertension||Li Xuyan|Beijing Chao Yang Hospital||April 2020||Not Applicable|
|NCT04099485||Not yet recruiting||Other: Electronic Health Record Best Practice Advisory||Atrial Fibrillation||University of Cincinnati||April 1 2020||Not Applicable|
|NCT04052243||Not yet recruiting||Diagnostic Test: Invasive exercise testing||Chronic Thromboembolic Pulmonary Hypertension||Aarhus University Hospital|Nagoya University|Department of Pulmonary Circulation and Thromboembolic Diseases Medical Center for Postgraduate Med||January 1 2020||Not Applicable|
|NCT03932487||Recruiting||Other: urinary iodine and urine BPA||The Effect of Iodine and BPA on AITD in Reproduction Women||Xiaomei Zhang|Peking University International Hospital||June 24 2019||--|
|NCT03361137||Terminated||Drug: Emicizumab||Hemophilia A||Genentech Inc.||June 28 2018||Phase 4|
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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