CAS No. 1157-39-7

Batch: Purity:99.82
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4',7-Dimethoxyisoflavone Chemical Structure
Chemical Structure
Check the 4',7-Dimethoxyisoflavone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 7-methoxy-3-(4-methoxyphenyl)chromen-4-one
CAS Number 1157-39-7
Molecular Formula

C17H14O4
Molecular Weight (MW) 282.29
SMILES COC1=CC=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)OC
InChIKey LPNBCGIVZXHHHO-UHFFFAOYSA-N

Biological Activity

4',7-Dimethoxyisoflavone is a natural plant-derived isoflavone that functions as an antifungal agent. Isolated from the leaves of Albizzia lebbeck, this compound displays in vitro antifungal activity by inhibiting fungal growth and cellular proliferation. As a methoxylated flavonoid derivative, it alters fungal metabolic and structural pathways, contributing to the disruption of fungal cell membrane integrity and pathogen survival. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 4 mg/mL (14.16 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Cushnie TP, et al. Int J Antimicrob Agents. 2005;26(5):343-56.

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Note: Technical data last updated: Sep 1, 2026.