CAS No. 621-44-3
Batch:
Purity:99.50
Chemical Structure
Check the
3-Nitro-L-tyrosine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (2S)-2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid | |
|---|---|---|
| CAS Number | 621-44-3 | |
| Molecular Formula |
C9H10N2O5 |
|
| Molecular Weight (MW) | 226.19 | |
| SMILES | NC(CC1=CC(=C(O)C=C1)[N+]([O-])=O)C(O)=O | |
| InChIKey | FBTSQILOGYXGMD-LURJTMIESA-N |
3-Nitro-L-tyrosine is a nitrated amino acid derivative generated from L-tyrosine reaction with peroxynitrite, a reactive species formed by nitric oxide and superoxide. As a biomarker and mediator of oxidative and nitrative stress, it inhibits hemodynamic responses induced by angiotensin II, potentially through the attenuation of alpha 1-adrenoceptor-mediated signaling pathways, thereby modulating vascular tone and arterial blood pressure regulation. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
2 mg/mL
(8.84 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
| Water | 1 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- 3-Nitro-L-tyrosine Clinical Trials
- 3-Nitro-L-tyrosine Solubility in DMSO
- 3-Nitro-L-tyrosine Stock Solution
- 3-Nitro-L-tyrosine Storage
- 3-Nitro-L-tyrosine Stability
- 3-Nitro-L-tyrosine Molecular Weight
- 3-Nitro-L-tyrosine SMILES
- 3-Nitro-L-tyrosine Chemical Structure (2D and 3D)
- 3-Nitro-L-tyrosine SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.