CAS No. 1453-58-3

Batch: Purity:
3-Methylpyrazole Chemical Structure
Chemical Structure
Check the 3-Methylpyrazole product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 5-methyl-1H-pyrazole
CAS Number 1453-58-3
Molecular Formula

C4H6N2

Molecular Weight (MW) 82.10
SMILES CC1=CC=NN1
InChIKey XKVUYEYANWFIJX-UHFFFAOYSA-N

Ordering Information

Biological Activity

3-Methylpyrazole (3-MP) is a pyrazole derivative that acts as a weak or non-inhibitor of alcohol dehydrogenase (ADH). Unlike its structural isomer 4-methylpyrazole, 3-methylpyrazole displays negligible binding affinity and minimal inhibitory activity against liver ADH. Consequently, it exerts little to no effect on ADH-mediated alcohol oxidation or downstream NAD+/NADH-dependent metabolic processes, serving as a structural contrast in enzyme-inhibitor relationship studies.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.