CAS No. 1477-68-5

Batch: Purity:99.07
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3-Methoxytyramine hydrochloride Chemical Structure
Chemical Structure
Check the 3-Methoxytyramine hydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1477-68-5
Molecular Formula

C9H14ClNO2
Molecular Weight (MW) 203.67
SMILES Cl.COC1=C(O)C=CC(=C1)CCN

Ordering Information

Biological Activity

3-Methoxytyramine hydrochloride is a major extracellular dopamine metabolite and active neuromodulator that targets trace amine-associated receptor 1 (TAAR1). It modulates catecholaminergic signaling and downstream neuronal signaling pathways to regulate movement control. Publicly reported data indicate that 3-methoxytyramine acts as an endogenous functional ligand affecting motor activity and behavioral responses through TAAR1-dependent signaling mechanisms. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 40 mg/mL (196.39 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 40 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.