CAS No. 99-06-9

Batch: Purity:99
3-Hydroxybenzoic acid Chemical Structure
Chemical Structure
Check the 3-Hydroxybenzoic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 99-06-9
Molecular Formula

C7H6O3

Molecular Weight (MW) 138.12
SMILES C1=CC(=CC(=C1)O)C(=O)O

Biological Activity

3-Hydroxybenzoic acid is a monohydroxybenzoic acid derivative that functions as an antioxidant and metabolic intermediate. It modulates cellular redox homeostasis by scavenging free radicals and inhibiting lipid peroxidation in biological membranes. Through its interference with oxidative stress pathways, 3-hydroxybenzoic acid protects cellular components against oxidative damage and maintains metabolic cellular stability. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 28 mg/mL (202.72 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

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Note: Technical data last updated: Sep 1, 2026.