CAS No. 100-83-4
Batch:
Purity:99.9
Chemical Structure
Check the
3-Hydroxybenzaldehyde
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 100-83-4 | |
|---|---|---|
| Molecular Formula |
C7H6O2 |
|
| Molecular Weight (MW) | 122.12 | |
| SMILES | OC1=CC=CC(=C1)C=O |
Biological Activity
3-Hydroxybenzaldehyde (3-HBA) is a naturally occurring benzaldehyde derivative that acts as a substrate for aldehyde dehydrogenase 2 (ALDH2). It exhibits notable vasculoprotective and antioxidant activities by suppressing reactive oxygen species production and attenuating vascular smooth muscle cell migration and proliferation. Through these cellular pathways, 3-Hydroxybenzaldehyde protects vascular endothelial cells against oxidative stress-induced damage and modulates vascular remodeling phenotypes. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
24 mg/mL
(196.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 24 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.