CAS No. 117060-54-5

Batch: Purity:99.98
3'-hydroxy Puerarin Chemical Structure
Chemical Structure
Check the 3'-hydroxy Puerarin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 117060-54-5
Molecular Formula

C21H20O10

Molecular Weight (MW) 432.38
SMILES OCC1OC(C(O)C(O)C1O)C2=C(O)C=CC3=C2OC=C(C3=O)C4=CC(=C(O)C=C4)O

Ordering Information

Biological Activity

3'-hydroxy Puerarin is a natural C-glycosylisoflavone isolated from Puerariae Lobatae Radix that exhibits potent antioxidant and cytoprotective activities. It functions by scavenging reactive oxygen species (ROS) and suppressing oxidative stress-induced apoptosis in neuronal and vascular cell types. Additionally, 3'-hydroxy Puerarin modulates key intracellular cascades, including the NF-kB and MAPK signaling pathways, leading to reduced expression of pro-inflammatory cytokines and inhibition of cellular injury. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (231.27 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.